A pré-medicação com midazolam antes de secção cesariana não tem efeitos adversos no neonato

Ahmet Can Senel; Fatih Mergan

doi:10.1016/j.bjan.2012.08.003

Scientific Article

A pré-medicação com midazolam antes de secção cesariana não tem efeitos adversos no neonato

Premedication with midazolam prior to caesarean section has no neonatal adverse effects

Ahmet Can Senel; Fatih Mergan

http://dx.doi.org/10.1016/j.bjan.2012.08.003 Braz J Anesthesiol, vol.64, n1, p.16-21, 2014

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Resumo

Como todos os pacientes cirúrgicos, pacientes obstétricas também sentem estresse e ansieda de operatórios. Isso pode ser prevenido se forem passadas à paciente informações detalhadas sobre sua operação e se forem administrados medicamentos farmacológicos pré-operatórios. Devido aos efeitos depressivos dos sedativos nos neonatos, os medicamentos farmacológicos são omitidos, especialmente em pacientes obstétricas. A literatura contém poucos estudos concernentes ao uso de midazolam no pré-operatório em pacientes de secção cesariana (C/S). Nosso objetivo nesse estudo foi ajudar nossas pacientes passando por cirurgia C/S. Um grupo agendado para C/S eletiva recebeu midazolam 0,025 mg kg−1 por via intraveno sa; o outro grupo recebeu salina. A ansiedade materna foi avaliada com o uso dos escores da Amsterdam Preoperative Anxiety and Information Scale (APAIS) (Escala de Ansiedade e Informação Pré-operatória de Amsterdam), e os neonatos foram avaliados por Apgar e pelo instrumento Neonatal Neurologic and Adaptive Capacity Score (NACS) (Escore Neurológico e de Capacidade Adaptativa do Neonato). Em conclusão, os pacientes pré-medicados com midazolam 0,025 mg kg−1 medicação tiveram escores de ansiedade significativamente baixos, sem qualquer efeito adverso nos neonatos. Portanto, midazolam pode, com segurança, ser utilizado como agente de pré-medicação na cirurgia C/S.

Palavras-chave

Secção cesariana, Neonato, Pré-medicação, Midazolam

Abstract

Like all surgical patients, obstetric patients also feel operative stress and anxiety. This can be prevented by giving patients detailed information about their operation and with preoperative pharmacological medications. Because of depressive effects of sedatives on newborns, pharmacological medications are omitted, especially in obstetric patients. The literature contains few studies concerning preoperative midazolam use in Caesarian section (C/S) patients. Our aim in this study was to help patients undergoing C/S surgery. One group scheduled for elective C/S received midazolam 0.025 mg kg-1 intravenously, the other received saline. Maternal anxiety was evaluated using Amsterdam Preoperative Anxiety and Information Scale (APAIS) scores, and newborns were evaluated using Apgar and the Neonatal Neurologic and Adaptive Capacity Score (NACS). In conclusion, patients receiving midazolam 0.025 mg kg-1 as premedication had significantly low anxiety scores, without any adverse effects on the newborns. Midazolam can therefore safely be used as a premedicative agent in C/S surgery.

Keywords

Cesarean section, Newborn, Premedication, Midazolam

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A pré-medicação com midazolam antes de secção cesariana não tem efeitos adversos no neonato

Premedication with midazolam prior to caesarean section has no neonatal adverse effects

Ahmet Can Senel; Fatih Mergan

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