Brazilian Journal of Anesthesiology
https://bjan-sba.org/article/doi/10.1590/S0034-70942012000600001
Brazilian Journal of Anesthesiology
Scientific Article

Raquianestesia com dose baixa da combinação de bupivacaína e fentanil: uma boa alternativa para a cirurgia de ressecção transuretral de próstata em pacientes idosos em regime ambulatorial

Spinal anesthesia with low-dose bupivacaine-fentanyl combination: a good alternative for day case transurethral resection of prostrate surgery in geriatric patients

Zeynep N Akcaboy; Erkan Y Akcaboy; Nevzat M Mutlu; Nurten Serger; Cuneyt Aksu; Nermin Gogus

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Resumo

JUSTIFICATIVA E OBJETIVOS: Avaliar a eficácia, a duração do bloqueio, a permanência na sala de recuperação pós-anestesia e os efeitos adversos do uso por via intratecal de doses baixas de bupivacaína em combinação com fentanil e compará-los com a dose convencional de prilocaína e fentanil em cirurgia de ressecção transuretral de próstata em pacientes idosos em regime ambulatorial. MATERIAIS E MÉTODOS: Foram randomicamente designados 60 pacientes para dois grupos: o Grupo B recebeu 4 mg de bupivacaína a 0,5% + 25 µg de fentanil e o Grupo P recebeu 50 mg de prilocaína a 2% + 25 µg de fentanil intratecal. Qualidade e duração dos bloqueios, tempo de permanência na sala de recuperação pós-anestésica e efeitos adversos foram comparados. RESULTADOS: A duração do bloqueio e o tempo de permanência na sala de recuperação pós-anestésica foram menores no Grupo B do que no Grupo P (p < 0,001 para ambos). Hipotensão e bradicardia não foram observadas no Grupo B, que foi significativamente diferente do Grupo P (p = 0,024, p = 0,011, respectivamente). CONCLUSÃO: A administração intratecal de 4 mg de bupivacaína + 25 µg de fentanil forneceu raquianestesia adequada com menos tempo de duração do bloqueio e de permanência na sala de recuperação pós-anestésica com perfil hemodinâmico estável comparado à administração intratecal de 50 mg de prilocaína + 25 µg de fentanil para cirurgia de ressecção transuretral de próstata em pacientes idosos em regime ambulatorial.

Palavras-chave

ANESTESIA, Regional, subaracnóide, ANESTÉSICOS, Local, bupivacaína, prilocaína, CIRURGIA, Urológica

Abstract

BACKGROUND AND OBJECTIVE: We evaluated the effectiveness, block duration, postanesthesia care unit stay and adverse effects of using intrathecal low dose bupivacaine and fentanyl combination and compared with conventional dose prilocaine and fentanyl combination for day case transurethral resection of prostate surgery in geriatric patient population. MATERIALS AND METHODS: Sixty patients were randomized into two groups with Group B receiving 4 mg bupivacine 0.5% + 25 µg fentanyl and Group P receiving 50 mg prilocaine 2% + 25 µg fentanyl intrathecal. Block quality and duration, postanesthesia care unit stay and adverse effects were compared. RESULTS: Block durations and postanesthesia care unit stay were shorter in Group B than in Group P (p < 0.001 in both). Hypotension and bradycardia were not seen in Group B which was significantly different than in Group P (p = 0.024 and p = 0.011 respectively). CONCLUSION: Intrathecal 4 mg bupivacaine + 25 µg fentanyl provided adequate spinal anesthesia with shorter block duration and postanesthesia care unit stay with stable hemodynamic profile than intrathecal 50 mg prilocaine + 25 µg fentanyl for day case transurethral resection of prostate surgery in geriatric patients.

Keywords

Anesthesia, Spinal, Bupivacaine, Prilocaine, Transurethral Resection of Prostate

References

Kararmaz A, Kaya S, Turhanoglu S, Ozyılmaz MA. Low dose bupivacaine-fentanyl spinal anesthesia for transurethral prostatectomy. Anaesthesia. 2003:526-530.

Hole A, Terjesen T, Breivig H. Epidural versus general anesthesia for total hip artroplasty in elderly patients. Acta Anaesthesiol Scand. 1980;24:279-287.

Rubin AP. Spianal anesthesia. Principles and Practice of Regional Anesthesia. 1998:70-80.

Hampl K, Scheneider M, Ummenhofer W, Drewe J. Transient neurologic symptoms after spinal anesthesia. Anesth Analg. 1995;81.

Ostgaard G, Hallaraker O, Ulveseth OK, Flaaten H. A randomized study of lidacaine and prilocaine for spinal anesthesia. Acta Anaesthesiol Scand. 2000;44:436-440.

De Weert K, Traksel M, Gielen M, Slappendel R, Weber E, Dinksen R. The incidence of transient neurological symptoms after spinal anesthesia with lidocaine compared to prilocaine. Anaesthesia. 2000;55:1020-1024.

Hendriks MP, de Weert CJM, Snoeck MMJ, Hu HP, Pluim MAL, Gielen MJM. Plain articaine or prilocaine for spinal anesthesia in day case knee arthroscopy: a double blind randomized trial. Br J Anaesth. 2009;102:259-263.

Liu SS, Ware PD, Allen HW, Neal JM, Pollock JE. Dose response characteristics of spinal bupivacaine in volunteers. Anesthesiology. 1996;85:729-736.

Akcaboy EY, Akcaboy ZN, Gogus N. Low-dose levobupivacaine 0.5% with fentanyl in spinal anesthesia for transurethral resection of prostate surgery. JRMS. 2011;16:68-73.

Beers RA, Kane PB, Nsouli I, Krauss D. Does a mid-lumbar block level provide adequate anesthesia for transurethral prostatectomy?. Can J Anaesth. 1994;41:807-812.

Malhotra V, Diwan S. Anesthesia for the renal and genitourinary systems. Anesthesia. 2000.

Kuusniemi KS, Pihlajamaki KK, Pitkanen MT, Helenius HY, Kirvela OA. The use of bupivacaine and fentanyl for spinal anesthesia for urologic surgery. Anesth Analg. 2000;91:1452-1456.

Critchley LA. Hypotension, subarachnoid block and the elderly patient. Anaesthesia. 1996;51:1139-1143.

Rooke GA, Freund PR, Jacobson AF. Hemodynamic response and change in organ blood volume during spinal anesthesia in elderly men with cardiac disease. Anesth Analg. 1997;85:99-105.

Erdil F, Bulut S, Demirbilek S, Gedik E, Gulhas N, Ersoy MO. The effects of intrathecal levobupivacaine and bupivacaine in the elderly. Anaesthesia. 2009;64:942-946.

Reisli R, Celik S, Tuncer S, Yosunkaya A, Otelcioglu S. Anesthetic and hemodynamic effects of continuous spinal versus continuous epidural anesthesia with prilocaine. Eur J Anaesthesiol. 2003;20:26-33.

Nair GS, Abrishami A, Lernitte J, Chung F. Systematic review of spinal anesthesia using bupivacaine for ambulatory knee arthroscopy. Br J Anaesth. 2009;102:307-315.

Owen MD, Ozsarac O, Sahin S, Uckunkaya N, Kaplan N, Magunaci I. Low-dose clonidine and neostigmine prolong duration of intrathecal bupivacaine-fentanyl for labor analgesia. Anesthesiology. 2000;92:361-366.

Sarvela PJ, Halonen PM, Korttila KT. Comparison of 9 mg of intrathecal plain and hyperbaric bupivacaine both with fentanyl for cesarean delivery. Anesth Analg. 1999;89:1257-1262.

Wang C, Chakrabarti MK, Whitwam JG. Specific enhancement by fentanyl of the effects of intrathecal bupivacaine on nociceptive afferent but not on sympathetic efferent pathways in dogs. Anesthesiology. 1993;79:766-773.

Goel S, Bhardwaj N, Grover VK. Intrathecal fentanyl added to intrathecal bupivacaine for day case surgery: a randomized study. Eur J Anaesthesiol. 2003;20:294-297.

Biboulet P, Deschodt J, Aubas P, Vacher E, Chauvet P, D'Athis F. Continuous spinal anesthesia: does low-dose plain or hyperbaric bupivacaine allow the performance of hip surgery in the elderly?. Reg Anesth Pain Med. 1993;18:170-175.

Chow TC, Cho PH. The influence of small dose intrathecal fentanyl on shivering during transurethral resection of prostate under spinal anesthesia. Acta Anaesth Sinica. 1994;32:165-170.

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