Brazilian Journal of Anesthesiology
https://bjan-sba.org/article/doi/10.1590/S0034-70942012000400011
Brazilian Journal of Anesthesiology
Review Article

Anestesia e retalhos microvascularizados

Anesthesia and surgical microvascular flaps

Cláudia Margarida Brito Pereira; Maria Eduarda Leite Figueiredo; Rita Carvalho; Dora Catre; José Pedro Assunção

Downloads: 3
Views: 847

Resumo

JUSTIFICATIVA E OBJETIVOS: A cirurgia reconstrutiva de cabeça e pescoço representa um grande desafio perante a necessidade de se conseguir um bom resultado estético e funcional. A anestesia pode ser um fator importante e determinante no sucesso da técnica dado o seu papel na estabilidade hemodinâmica e no fluxo de sangue regional. Por outro lado, a anestesia regional, as variações no volume sanguíneo e o uso de fármacos vasoativos podem também influenciar o fluxo de sangue no retalho. Assim, devido à falta de recomendações baseadas em evidência, a técnica anestésica destes procedimentos é inspirada na maioria das vezes nas considerações patofisiológicas. O objetivo deste artigo é rever os aspectos relevantes no que diz respeito à prática anestésica destes casos. CONTEÚDO: Importância do tipo do retalho, considerações fisiológicas e abordagem anestésica. CONCLUSÕES: O papel do anestesiologista inclui para cirurgia com retalhos microvasculares a otimização das condições fisiológicas para a sobrevida do retalho sem aumentar a morbidade não cirúrgica.

Palavras-chave

ANESTESIA, CIRURGIA, Vascular, Retalhos Cirúrgicos

Abstract

BACKGROUND AND OBJECTIVES: Head and neck reconstructive surgery represents a major challenge facing the need to achieve a good cosmetic and functional outcome. Anesthesia may be an important and determining factor in the technique success due to its role in hemodynamic stability and regional blood flow. On the other hand, regional anesthesia, changes in blood volume, and vasoactive drugs may influence blood flow in the flap. Thus, due to the lack of recommendations based on evidence, the anesthetic technique of these procedures is most often inspired in pathophysiological considerations. The aim of this paper is to review relevant aspects regarding anesthetic practice in these cases. CONTENT: Importance of the type of surgical flap, physiological considerations, and anesthetic approach. CONCLUSIONS: In surgery with microvascular flaps, the anesthesiologist role includes optimizing the physiological conditions for the survival of the flap without increasing the non-surgical morbidity.

Keywords

Anesthesia, Surgical Flaps, Vascular Surgical Procedures

References

Nahabedian M. Flaps, free tissue transfer. 2008.

Hagau N, Longrois D. Anesthesia for free vascularised tissue transfer. Microsurgery. 2009;29:161-167.

Hidalgo DA, Jones CS. The role of emergent exploration in free tissue transfer: A review of 150 consecutive cases. Plast Reconstr Surg. 1990;86:492-499.

Adams J, Charlton P. Anesthesia for microvascular free tissue transfer. Br J Anaesth (CEPD Reviews). 2003;3:33-37.

Sigurdsson GH, Thomson D. Anesthesia and microvascular surgery: Clinical practice and research. Eur J Anaesthesiol. 1995;12:101-122.

Quinlan J. Anaesthesia for reconstrutive surgery. Anaesth Intensive Care. 2006;7:31-35.

Pushparaj S, Boyce H, Chisholm D. Curr Anaesth Crit Care. 2009;20:18-21.

Malata CM, Cooter RD, Batchelor AG. Microvascular free-tissue transfers in elderly patients: the Leeds experience. Plast Reconstr Surg. 1996;98:1234-1241.

Ozkan O, Ozgentas HE, Islamoglu K. Experiences with microsurgical tissue transfers in elderly patients. Microsurgery. 2005;25:390-395.

Serletti JM, Higgins JP, Moran S. Factors affecting outcome in free tissue transfer in the elderly. Plast Reconstr Surg. 2000;106:66-70.

Coskunfirat OK, Chen HC, Spanio S. The safety of microvascular free tissue transfer in the elderly population. Plast Reconstr Surg. 2005;115:771-775.

Khouri R, Cooley BC, Kunselman AR. A prospective study of microvascular free flap surgery and outcome. Plast Reconstr Surg. 1998;102:711-721.

Klug C, Berzaczy D, Reinbacher H. Influence of previous radiotherapy on free tissue transfer in the head and neck region: evaluation of 455 cases. Laryngosope. 2006;116:1162-1167.

Chiang S, Cohen B, Blackwell K. Myocardial infarction after microvascular head and neck reconstruction. Laryngoscope. 2002;112:1849-1852.

Chang DW, Reece GP, Wang B. Effect of smoking on complications in patients undergoing free TRAM flap breast reconstruction. Plast Reconstr Surg. 2000;105:2374-2380.

Spear SL, Ducic I, Cuoco F. The effect of smoking on flap and donor site complications in pedicled TRAM breast reconstruction. Plast Reconstr Surg. 2005;116:1873-1880.

Kuri M, Nakagawa M, Tanaka H. Determination of the duration of perioperative smoking cessation to improve wound healing after head and neck surgery. Anesthesiology. 2005;102:892-896.

Scalia R, Gong Y, Berzins B. Hyperglycemia is a major determinant of albumin permeability in diabetic microcirculation: The role of l-Calpain. Diabetes. 2007;56:1842-1849.

Chang DW, Wang B, Robb GL. Effect of obesity on flap and donor-site complications in free transverse rectus abdominis myocutaneous flap breast reconstruction. Plast Reconstr Surg. 2000;105:1640-1648.

Awwad AM, White RJ, Webster MH. The effect of temperature on blood flow in island and free skin flaps: an experimental study. Br J Plast Surg. 1983;36:373-382.

Myles PS, Leslie K, Chan MT. Avoidance of nitrous oxide for patients undergoing major surgery: a randomized controlled trial. Anesthesiology. 2007;107:221-231.

Myles PS, Chan MT, Leslie K. Effect of nitrous oxide on plasma homocysteine and folate in patients undergoing major surgery. Br J Anaesth. 2008;100:780-786.

Hahn RG. Microvascular changes and anesthesia. Acta Anaesthesiol Scand. 2002;46:479-480.

Bruegger D, Bauer A, Finsterer U. Microvascular changes during anesthesia: Sevoflurane compared with propofol. Acta Anaesthesiol Scand. 2002;46:481-487.

Lucchinetti E, Ambrosio S, Aguirre J. Sevoflurane inhalation at sedative concentrations provides endothelial protection against ischemia-reperfusion injury in humans. Anesthesiology. 2007;106:262-268.

Bertuglia S, Colantuoni A, Coppini G. Hypoxia- or hyperoxia-induced changes in arteriolar vasomotion in skeletal muscle microcirculation. Am J Physiol Heart Circ Physiol. 1991;260:H362-H372.

Messina EJ, Sun D, Koller A. Increases in oxygen tension evoke arteriolar constriction by inhibiting endothelial prostaglandin synthesis. Microvasc Res. 1994;48:151-160.

Tsai AG, Cabrales P, Winslow RM. Microvascular oxygen distribution in awake hamster window chamber model during hyperoxia. Am J Physiol Heart Circ Physiol. 2003;285:H1537- H1545.

Sigurdsson GH. Perioperative fluid management in microvascular surgery. J Reconstr Microsurg. 1995;11:57-65.

Pohlenz P, Blessmann M, Heiland M. Postoperative complications in 202 cases of microvascular head and neck reconstruction. J Craniomaxillofac Surg. 2007;35:311-315.

Hébert PC, Wells G, Blajchman MA. A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care: Transfusion Requirements in Critical Care Canadian Critical Care Trials. N Engl J Med. 1999;11:409-417.

Skoner JM, Wax MK. Microvascular free-tissue transfer for head and neck reconstruction in Jehovah's Witness patients. Head Neck. 2008;30:455-460.

Banic A, Krejci V, Erni D. Effects of sodium nitroprusside and phenylephrine on blood flow in free musculocutaneous flaps during general anesthesia. Anesthesiology. 1999;90:147-155.

Jones SJ, Scott DA, Watson R. Milrinone does not improve free flap survival in microvascular surgery. Anaesth Intensive Care. 2007;35:720-725.

Weinzweig N, Lukash F. Topical and systemic calcium channel blockers in the prevention and treatment of microvascular spasm in a rat epigastric island skin flap model. J Ann Plast Surg. 1999;42:320-326.

Rodrı´guez Vegas JM, Ruiz Alonso ME, Tera´n Saavedra PP. PGE-1 in replantation and free tissue transfer: early preliminary experience. Microsurgery. 2007;27:395-397.

Banic A, Krejci V, Erni D. Effects of extradural anesthesia on microcirculatory blood flow in free latissimus dorsi musculocutaneous flaps in pigs. Plast Reconstr Surg. 1997;100:945-955.

Massey MF, Gupta DK. The effects of systemic phenylephrine and epinephrine on pedicle artery and microvascular perfusion in a pig model of myoadipocutaneous rotational flaps. Plast Reconstr Surg. 2007;120:1289-1299.

Suominen S, Svartling N, Silvasti M. The effect of intravenous dopamine and dobutamine on blood circulation during amicrovascular TRAM flap operation. Ann Plast Surg. 2004;53:425-431.

Chen CM, Ashjian P, Disa JJ. Is the use of intraoperative heparin safe?. Plast Reconstr Surg. 2008;121:49e-53e.

Chien W, Varvares MA, Hadlock T. Effects of aspirin and low-dose heparin in head and neck reconstruction using microvascular free flaps. Laryngoscope. 2005;115:973-976.

Moore MG, Deschler DG. Clopidogrel (Plavix) reduces the rate of thrombosis in the rat tuck model for microvenous anastomosis. Otolaryngol Head Neck Surg. 2007;136:573-576.

Panchapakesan V, Addison P, Beausang E. Role of thrombolysis in free-flap salvage. J Reconstr Microsurg. 2003;19:523-530.

Bhatnagar S, Saxena A, Kannan TR. Tramadol for postoperative shivering: a double-blind comparison with pethidine. Anaesth Intensive Care. 2001;29:149-154.

Chen KT, Mardini S, Chuang DC. Timing of presentation of the first signs of vascular compromise dictates the salvage outcome of free flap transfers. Plast Reconstr Surg. 2007;120:187-195.

Rosenberg JJ, Fornage BD, Chevray PM. Monitoring buried free flaps: limitations of the implantable Doppler and use of color duplex sonography as a confirmatory test. Plast Reconstr Surg. 2006;118:109-113.

5dd2aba70e8825bb74c63493 rba Articles
Links & Downloads

Braz J Anesthesiol

Share this page
Page Sections