Brazilian Journal of Anesthesiology
https://bjan-sba.org/article/doi/10.1590/S0034-70942010000400012
Brazilian Journal of Anesthesiology
Review Article

Efeitos do propofol sobre o sistema de condução cardíaca

Effects of propofol on the cardiac conduction system

Paulo Warpechowski; Ari Tadeu Lírio dos Santos; Paulo José Irigon Pereira; Gustavo Glotz de Lima

http://dx.doi.org/10.1590/S0034-70942010000400012 Braz J Anesthesiol, vol.60, n4, p.441-444, 2010
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Resumo

JUSTIFICATIVA E OBJETIVOS: Alguns estudos têm demonstrado que o uso do propofol é, algumas vezes, associado a bradiarritmias ou reversão de arritmias para ritmo sinusal. Essa propriedade do propofol sugere interferência no Sistema de Condução Cardíaco (SCC). CONTEÚDO: Realizou-se revisão com base nos principais artigos contemporâneos que englobam o uso do propofol na presença de arritmias cardía cas. Os autores discorrem sobre os mecanismos fisiopatológicos das taquiarritmias supraventriculares (TSV) e as eventuais interferências causadas pelo propofol sobre o SCC. CONCLUSÕES: Os estudos realizados até então parecem indicar que, provavelmente, o propofol interfere nas TSV automáticas (pelo menos em crianças), mas não nas taquiarritmias em que o mecanismo seja de reentrada.

Palavras-chave

ANESTÉSICOS, Venoso, COMPLICAÇÕES

Abstract

BACKGROUND AND OBJECTIVES: Some studies have demonstrated that the use of propofol is occasionally associated with bradyarrhythmias or reversion of arrhythmias to sinus rhythm. This property of propofol suggests interference with the Cardiac Conduction System (CCS). CONTENTS: A review of the main contemporary articles on the use of propofol in the presence of cardiac arrhythmias was undertaken. The authors describe pathophysiological mechanisms of supraventricular tachyarrhythmias (SVT) and occasional interferences caused by propofol on the CCS. CONCLUSIONS: The studies undertaken so far seem to indicate that propofol probably interferes in automatic SVT (at least in children), but not in reentrant tachyarrhythmias.

Keywords

ANESTHETICS, Intravenous, COMPLICATIONS

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