Brazilian Journal of Anesthesiology
https://bjan-sba.org/article/doi/10.1590/S0034-70942008000500004
Brazilian Journal of Anesthesiology
Scientific Article

Incidência e profilaxia de náuseas e vômitos na recuperação pós-anestésica de um hospital-escola terciário

Incidence and prophylaxis of nausea and vomiting in post-anesthetic recovery in a tertiary teaching hospital

César Augusto Martins Patti; Joaquim Edson Vieira; Fábio Ely Martins Benseñor

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Resumo

JUSTIFICATIVA E OBJETIVOS: Náuseas e vômitos pós-operatórios (NVPO) constituem complicação freqüente e potencialmente grave que aumenta o tempo de recuperação pós-anestésica (RPA) e implica insatisfação dos pacientes. Avaliação do risco para NVPO e instituição de profilaxia visando ao bem-estar dos pacientes e à redução de custos têm sido freqüentes em publicações médicas. Este estudo observacional avaliou a incidência, fatores de risco e adequação e efetividade da profilaxia para NVPO na RPA de um hospital-escola terciário. MÉTODO: As informações obtidas a partir de prontuários e questionários aplicados aos pacientes incluíram idade, fatores preditivos maiores para NVPO (sexo feminino, história prévia, não-tabagismo, uso pós-operatório de opióides), profilaxia administrada, ocorrência de NVPO, tipo de cirurgia e anestesia, utilização de óxido nitroso, estado clínico e tempo de permanência na RPA. RESULTADOS: Observou-se incidência de 18,5% de náuseas e 8,5% de vômitos no pós-operatório imediato. Observou-se, ainda, correlação entre fatores maiores de risco e ocorrência de NVPO. Não se observou correlação entre tais fatores e a utilização de medicação antiemética profilática, bem como entre sua utilização e a ocorrência de NVPO. Contudo, observou-se tendência à administração de medicação profilática em pacientes jovens do sexo feminino. CONCLUSÕES: A preocupação dos anestesiologistas da instituição com NVPO ficou estabelecida. Contudo, a ausência de correlação entre risco e profilaxia sugere realização empírica e pouco efetiva. Fatores não-avaliados são sugeridos pela ausência de correlação entre NVPO e o uso de antieméticos. Orientação dos anestesiologistas quanto a condutas profiláticas mais eficientes pode aprimorar os cuidados à população atendida.

Palavras-chave

COMPLICAÇÕES, DROGAS, RECUPERAÇÃO PÓS-ANESTÉSICA

Abstract

BACKGROUND AND OBJECTIVES: Postoperative nausea and vomiting (PONV) is frequent and potentially a severe complication that increases the length of anesthetic recovery and causes patient dissatisfaction. The evaluation of the risk of PONV and institution of prophylactic measures aiming the well-being of patients and cost reduction are frequent in the medical literature. This observational study evaluated the incidence, risk factors, and adjustment and effectivity of the prophylaxis of PONV in the recovery room of a tertiary teaching school. METHODS: Information obtained from patients' records and questionnaires answered by patients included age, major predictive factors for PONV (female gender, history, absence of smoking, and postoperative use of opioids), prophylactic drugs administered, development of PONV, type of surgery and anesthesia, use of nitrous oxide, clinical status, and length of stay in the recovery room. RESULTS: An incidence of 18.5% of nausea and 8.5% of vomiting in the immediate postoperative period was observed. A correlation between major risk factors and the development of PONV was also observed. A correlation between those factors and prophylactic anti-emetic drugs, as well as between their use and the development of PONV, was not observed. However, a tendency to administer prophylactic medication to young female patients was observed. CONCLUSIONS: The concerns of the anesthesiologists of the institution with PONV were evident. However, the absence of correlation between risk and prophylaxis suggests an empirical and ineffective procedure. Factors that were not evaluated were suggested by the absence between PONV and the use of anti-emetic drugs. The orientation for anesthesiologists regarding more effective prophylactic measures can improve care of the population assisted.

Keywords

COMPLICATIONS, DRUGS, POSTANESTHETIC RECOVERY

References

Abreu MP. Controle de Náuseas e Vômitos - Antieméticos. Tratado de Anestesiologia SAESP. 2006:1361-1372.

Neusa L, Cristina F, Aida N. Náuseas e vômitos no pós-operatório: uma revisão do "pequeno-grande " problema. Rev Bras Anestesiol. 2005;55:575-585.

Schmidt A, Bagatini A. Náusea e vômito pós-operatório: fisiopatologia, profilaxia e tratamento. Rev Bras Anestesiol. 1997;47:326-334.

Carvalho WA, Vianna PTG, Braz JRC. Náuseas e vômitos em anestesia: fisiopatologia e tratamento. Rev Bras Anestesiol. 1999;49:65-79.

Watcha MF, White PF. Postoperative nausea and vomiting: it´s etiology, treatment and prevention. Anesthesiology. 1992;77:162-184.

Kovac AL. Prevention and treatment of postoperative nausea and vomiting. Drugs. 2000;59:213-243.

Ku CM, Ong BC. Postoperative nausea and vomiting: a review of current literature. Singapore Med J. 2003;44:366-374.

Gold BS, Kitz DS, Lecky JH. Unanticipated admission to the hospital following ambulatory surgery. JAMA. 1989;262:3008-3010.

Eberhart LH, Morin AM, Wulf H. Patient preferences for immediate postoperative recovery. Brit J Anaesth. 2002;89:760-761.

Hill RP, Lubarsky DA, Phillips-Bute B. Cost-effectiveness of prophylactic antiemetic therapy with ondansetron, droperidol, or placebo. Anesthesiology. 2000;92:958-967.

Thomas R, Jones NA, Strike P. The value of risk scores for predicting postoperative nausea and vomiting when used to compare patient groups in a randomised controlled trial. Anaesthesia. 2002;57:1119-1128.

Sinclair DR, Chung F, Mezei G. Can postoperative nausea and vomiting be predicted?. Anesthesiology. 1999;91:109-118.

Gan TJ. Risk factors for postoperative nausea and vomiting. Anesth Analg. 2006;102:1884-1898.

Tramer MR. Treatment of postoperative nausea and vomiting. BMJ. 2003;327:762-763.

Eberhart LH, Hogel J, Seeling W. Evaluation of three risk scores to predict postoperative nausea and vomiting. Acta Anaesthesiol Scand. 2000;44:480-488.

Palazzo M, Evans R. Logistic regression analysis of fixed patient factors for postoperative sickness: a model for risk assessment. Brit J Anaesth. 1993;70:135-140.

Haigh CG, Kaplan LA, Durham JM. Nausea and vomiting after gynaecological surgery: a metanalisys of factors affecting their incidence. Brit J Anaesth. 1993;71:517-522.

Apfel CC, Roewer N, Korttila K. How to study postoperative nausea and vomiting. Acta Anaesthesiol Scand. 2002;46:921-928.

Apfel CC, Laara E, Koivuranta MD. A simplified risk score for predicting postoperative nausea and vomiting: conclusions from cross-validation between two centers. Anesthesiology. 1999;91:693-700.

Apfel CC, Greim CA, Haubitz I. A risk score to predict the probability of postoperative vomiting in adults. Acta Anaesthesiol Scand. 1998;42:495-501.

Apfel CC, Korttila K, Abdalla M. A factorial trial of six interventions for the prevention of postoperative nausea and vomiting. N Engl J Med. 2004;350:2441-2451.

Apfel CC, Kramke P, Eberhart LHJ. Comparison of predictive models for postoperative nausea and vomiting. Brit J Anaesth. 2002;88:234-240.

Gan TJ, Meyer T, Apfel CC. Consensus guidelines for managing postoperative nausea and vomiting. Anesth Analg. 2003;97:62-71.

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