Brazilian Journal of Anesthesiology
https://bjan-sba.org/article/doi/10.1590/S0034-70942005000300003
Brazilian Journal of Anesthesiology
Scientific Article

Avaliação da função renal do idoso em duas horas

Two-hour evaluation of renal function in the elderly

Maria do Carmo B. Sammartino Benarab; Yara Marcondes Machado Castiglia; Pedro Thadeu Galvão Vianna; José Reinaldo Cerqueira Braz

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Resumo

JUSTIFICATIVA E OBJETIVOS: Os idosos têm diminuição progressiva da função renal e os hipertensos, maior risco de lesão renal adicional no intra-operatório. Avalia-se a função renal pela depuração da creatinina, com débito urinário de 24 horas, para diluir o erro de possível volume vesical residual (VVR). O objetivo deste trabalho foi avaliar a função renal pré-operatória de idosos hipertensos e não-hipertensos, com débito urinário de duas horas, utilizando aparelho de ultra-som portátil para determinação do volume vesical residual. MÉTODO: Foram analisados 30 pacientes, distribuídos em dois grupos, Gn (15), idosos não-hipertensos, e Gh (15), idosos hipertensos, coletando-se urina durante 2 horas. Mediu-se o VVR com aparelho de ultra-som portátil. Analisaram-se os seguintes parâmetros: idade, sexo, estado físico, altura, peso, índice de massa corpórea, creatinina plasmática e urinária, sódio e potássio plasmáticos e urinários, osmolalidade plasmática e urinária, débito urinário, depuração da creatinina, osmolar e de água livre, excreção urinária e fracionária de sódio e potássio. Comparou-se a depuração estimada de creatinina com a depuração da creatinina. RESULTADOS: Os pacientes de Gn e Gh não apresentaram diferenças significativas quanto à maioria dos parâmetros estudados. Os idosos hipertensos apresentaram tendência a maior excreção fracionária de sódio e o potássio plasmático mostrou-se mais baixo nos hipertensos, porém com valores normais. A depuração estimada de creatinina correlacionou-se positivamente com a de creatinina apenas em Gn. CONCLUSÕES: Os pacientes hipertensos apresentaram potássio plasmático mais baixo e excretaram mais sódio, tendo ocorrido correspondência entre a depuração estimada de creatinina e a depuração da creatinina apenas para os pacientes do grupo dos não-hipertensos.

Palavras-chave

ANESTESIA, Geriátrica, DOENÇAS, SISTEMA RENAL

Abstract

BACKGROUND AND OBJECTIVES: Elderly have progressive renal function deterioration and hypertensive patients are at higher risk of additional intraoperative kidney injury. Renal function is evaluated by creatinine clearance, with 24-hour urinary output to dilute the error of possible residual vesical volume (RVV). This study aimed at evaluating preoperative renal function of hypertensive and normotensive elderly patients, with 2-hour urinary output, using portable ultrasound to determine residual vesical volume. METHODS: Participated in this study 30 patients distributed in 2 groups: Gn (15) normotensive elderly, and Gh (15) hypertensive elderly. Urine was collected for 2 hours. RVV was measured with portable ultrasound. The following parameters were evaluated: age, gender, physical status, height, weight, body mass index, plasma and urinary creatinine, plasma and urinary sodium and potassium, plasma and urinary osmolality, urinary output, creatinine, osmolar and free water clearance, sodium and potassium urinary and fractional excretion. Estimated creatinine clearance was compared to actual creatinine clearance. RESULTS: Gn and Gh patients were not significantly different in most evaluated parameters. Hypertensive elderly had a trend to higher sodium fractional excretion and plasma potassium was lower in hypertensive patients, however within normal ranges. Estimated creatinine clearance was positively correlated to actual creatinine clearance in Gn only. CONCLUSIONS: Hypertensive patients had lower plasma potassium and excreted more sodium, with correspondence between estimated and actual creatinine clearance in normotensive patients only.

Keywords

ANESTHESIA, Geriatric, DISEASES, RENAL SYSTEM

References

Zarnke KB, Levine M, McAlister FA. The 2000 Canadian recomendations for the management of hypertension: part two-Diagnosis and assessment of people with high blood pressure. Can J Cardiol. 2001;17:1249-1263.

Lote CJ, Harper L, Savage CO. Mechanisms of acute renal failure. Br J Anaesth. 1996;77:82-89.

Thadhani R, Pascual M, Bonventre JV. Acute renal failure. N Engl J Med. 1996;334:1448-1460.

Klahr S, Miller SB. Acute oliguria. N Engl J Med. 1998;338:671-675.

Sladen RN, Endo E, Harrison T. Two-hour versus 24-hour creatinine clearance in critically ill patients. Anesthesiology. 1987;67:1013-1016.

Stoller ML, Millard RJ. The accuracy of a catheterized residual urine. J Urol. 1989;141:15-16.

Cardenas DD, Kelly E, Krieger JN. Residual urine volumes in patients with spinal cord injury: measurement with a portable ultrasound instrument. Arch Phys Med Rehabil. 1988;69:514-516.

Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron. 1976;16:31-41.

Muravchick S. Anesthesia for the Elderly. Anesthesia. 2000:2140-2156.

Castiglia YMM, Vianna PTG. Monitorização da função renal. Rev Bras Anestesiol. 1992;42:85-89.

Laragh JH, Blumenfeld JD. Essential Hypertention. Brenner and Rector's the Kidney. 2000:1967-2006.

Hardman JG, Limbird LE. Goodman & Gilman's the Pharmacological Basis of Therapeutics. 2001.

Lye M. Body potassium content and capacity of elderly individuals with and without cardiac failure. Cardiovasc Res. 1982;16:22-25.

Oken DR. Hemodynamic basis for human acute renal failure (vasomotor nephropathy). Am J Med. 1984;76:702-710.

Brady HR, Brenner BM, Lieberthal W. Acute Renal Failure. Brenner and Rector's the Kidney. 1996:1200-1252.

Rolin HA, Hall PM, Wei R. Inaccuracy of estimate creatinine clearance for prediction of iothalamate glomerular filtration rate. Am J Kidney Dis. 1984;4:48-54.

Van den Noortgate NJ, Janssens WH, Afschrift MB. Renal function in the oldest-old on an acute geriatric ward. Int Urol Nephrol. 2001;32:531-537.

Fuse H, Yokoyama T, Muraishi Y. Measurement of residual urine volume using a portable ultrasound instrument. Int Urol Nephrol. 1996;28:633-637.

Klag MJ, Whelton PK, Randall BL. Blood pressure and end-stage renal disease in men. N Engl J Med. 1996;334:13-18.

Brenner BM, Meyer TW, Hostetter TH. Dietary protein intake and progressive nature of kidney disease: the role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation and intrinsic renal disease. N Engl J Med. 1982;307:652-659.

Marcantoni C, Jafar TH, Oldrizzi L. The role of systemic hypertension in the progression of nondiabetic renal disease. Kidney Int. 2000;75:Suppl):S44-S48.

Novis BK, Roizen MF, Aronson S. Association of preoperative risk factors with postoperative acute renal failure. Anesth Analg. 1994;78:143-149.

Star RA. Treatment of acute renal failure. Kidney Int. 1998;54:1817-1831.

Kellen M, Aronson S, Roizen MF. Predictive and diagnostic tests of renal failure: a review. Anesth Analg. 1994;78:134-142.

Zubicki A, Cittanova ML, Zaier K. Serum creatinine cannot predict renal impairment in the perioperative period. Br J Anaesth. 1998;80(^s1).

Cittanova ML. Is perioperative renal dysfunction of no consequence?. Br J Anaesth. 2001;86:164-166.

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