Brazilian Journal of Anesthesiology
https://bjan-sba.org/article/doi/10.1590/S0034-70942005000200010
Brazilian Journal of Anesthesiology
Miscellaneous

A serendipidade na medicina e na anestesiologia

Serendipity in medicine and anesthesiology

Nilton Bezerra do Vale; José Delfino; Lúcio Flávio Bezerra do Vale

http://dx.doi.org/10.1590/S0034-70942005000200010 Braz J Anesthesiol, vol.55, n2, p.224-249, 2005
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Resumo

JUSTIFICATIVA E OBJETIVOS: Neste trabalho foram examinados mais de uma centena dos mais felizes acoplamentos de uma mente brilhante com a sorte benfazeja (serendipidade), através da releitura das mais relevantes histórias sobre invenções e descobertas relacionadas à ciência (n = 46), à Medicina (n = 46) e à Anestesiologia (n = 16). CONTEÚDO: Conceito de serendipidade; exemplos célebres de serendipidade em Ciência e Tecnologia; serendipidade na pesquisa e prática médicas; serendipidade na Anestesiologia; serendipidade e criatividade na pesquisa. Através da história do desenvolvimento médico, a natureza provou que o caminho mais efetivo e mais barato na obtenção de drogas, instrumentos e serviços pode ser a sorte fortuita porque muitas descobertas são serendípticas. Este artigo educacional encoraja o anestesiologista a apreciar os eventos relacionados com invenções e descobertas científicas, mostrando-lhe que a serendipidade é possível, desde que seja aguardada. Cada descoberta ou invenção inclui história, biografia e explicação científica ou anedótica. Além das descobertas tradicionais como pão, vinho, gravidade, fotografia, velcro, air-bag, etc., há outras relacionadas à Medicina (microscópio, Raio X, vacina, penicilina, insulina, laser, esfregaço de Papanicolaou, etc.), e à Anestesiologia, como: isomeria, luvas, N2O, éter, barbitúrico, benzodiazepínicos, tampão sangüíneo, entre outros. Criatividade e serendipidade podem servir de linha mestra para pesquisa clínica e básica de invenções pioneiras para avanços médicos e anestesiológicos. Realmente, devem-se controlar tópicos relacionados com biologia, anatomia, física, química, fisiologia, farmacologia, astronomia, arqueologia e... muita sorte. CONCLUSÕES: Embora acidentes na pesquisa e na sala de operação sejam lamentáveis, há aqueles que acontecem e, às vezes, podem levar a avanços espetaculares, como tratamentos heróicos e até Prêmios Nobel. Manter a mente aberta é um traço comum àqueles que ensejam contar com a sorte grande, como afirmava o físico americano Henry (1842): "As sementes da descoberta flutuam constantemente à nossa volta, mas apenas lançam raízes nas mentes bem preparadas para recebê-las".

Palavras-chave

ANESTESIA, ANESTESIA, MEDICINA, SERENDIPIDADE

Abstract

BACKGROUND AND OBJECTIVES: This study has evaluated more than a hundred of the most fortunate couplings of a brilliant mind with fortunate luck (serendipity), through the re-reading of most relevant histories on science-related (n = 46) and anesthesiology-related (n = 16) inventions and discoveries. CONTENTS: This educational article encourages anesthesiologists to appreciate events related to scientific inventions and discoveries, showing that serendipity is possible, provided it is expected. Each discovery or invention includes history, references and scientific or anecdotal explanation. In addition to traditional discoveries, such as wine, gravity, photograph, Velcro, airbag, etc., there are other Medicine-related (microscope, X-rays, vaccine, penicillin, insulin, laser, Paps smear, etc.) and Anesthesiology-related (isometry, gloves, N2O, ether, barbiturates, benzodiazepines, blood patch, etc.) discoveries. Creativity and serendipity may act as cornerstones for clinical and basic research of pioneer inventions for medical and anesthesiologic advances. In fact, topics related to biology, anatomy, physics, chemistry, physiology, pharmacology, astronomy and archeology should be master and … lots of luck. CONCLUSIONS: Although research and operating room accidents are regrettable, some of them happen and may sometimes lead to spectacular advances, such as heroic treatments and even Nobel Prizes. Open-mindedness is a common trait to those willing to count on grand prize, as American physicist Henry would state (1842): "Seeds of discovery are constantly floating around us, but the onlytake roots in minds well prepared to receive them".

Keywords

ANESTHESIA, ANESTHESIA, MEDICINE, SERENDIPITY

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