Brazilian Journal of Anesthesiology
https://bjan-sba.org/article/doi/10.1590/S0034-70942004000200011
Brazilian Journal of Anesthesiology
Clinical Information

Analgesia regional periférica com lidocaína em paciente queimado: relato de caso

Peripheral regional analgesia with lidocaine in burned patient: case report

Karl Otto Geier

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Resumo

JUSTIFICATIVA E OBJETIVOS: A realização de anestesia regional em pacientes queimados é dificultosa pela localização aleatória das lesões térmicas. Elevadas taxas de alfa1 glicoproteína ácida com grande afinidade para drogas alcalinas, especialmente a lidocaína, têm sido observadas nesses pacientes. Este caso relata como o uso intermitente de anestesia e analgesia regional periférica com altas doses de lidocaína podem ser úteis em fornecer efetiva analgesia num paciente com queimaduras de segundo grau nos quatro membros, abrangendo, aproximadamente, 20% de área superficial queimada. RELATO DO CASO: Paciente do sexo masculino, 23 anos, 86 kg, estado físico ASA II, com queimadura superficial da face, segundo grau nos quatro membros e elevada taxa sérica de alfa1 glicoproteína ácida (260 mg.dl-1), teve sua dor controlada com 11,6 mg.kg-1 de lidocaína com adrenalina 1:400.000 administrada por cateteres introduzidos e tunelizados para diversos procedimentos - irrigações e troca de curativos, desbridamentos, fisioterapia, enxertos cutâneos e analgesia diária durante 28 dias. CONCLUSÕES: Em pacientes queimados com injúrias térmicas localizadas nas extremidades, a analgesia regional periférica pode ser útil. As elevadas taxas séricas de alfa1 glicoproteína ácida e o local da injeção podem permitir o emprego de altas doses de lidocaína.

Palavras-chave

ANESTÉSICOS, ANESTÉSICOS, TÉCNICAS ANESTÉSICAS, TÉCNICAS ANESTÉSICAS

Abstract

BACKGROUND AND OBJECTIVES: Regional anesthesia is difficult in burned patients due to the randomized location of thermal injuries. High plasma levels of alpha1-acid glycoprotein with major affinity to basic drugs, especially lidocaine, have been observed in these patients. This report shows how intermittent peripheral regional anesthesia and analgesia with high lidocaine doses may be useful in inducing effective analgesia in patient with almost 20% Total Burn Skin Area (TBSA) of partial thickness burn in his four limbs. CASE REPORT: Male patient, 23 years old, 86 kg, physical status ASA II, with superficial facial burn, partial thickness burn on four limbs and increased serum alpha1-acid glycoprotein levels (260 mg.dL-1), who was treated with 11.6 mg.kg-1 lidocaine with 1:400,000 epinephrine through catheters inserted and tunnelized, for several procedures - irrigations and dressing changes, débridements, physical therapy, skin grafting and daily analgesia during 28 days. CONCLUSIONS: Burned patients with thermal injuries on the extremities are suitable for peripheral regional analgesia. High alpha1-acid glycoprotein serum levels and injection site may allow the use of high lidocaine doses.

Keywords

ANESTHETICS, ANESTHETICS, ANESTHETIC TECHNIQUES, ANESTHETIC TECHNIQUES

References

Patel NJ, Flashburg MH, Paskin S. A regional anesthetic technique compared to general anesthesia for outpatient knee arthroscopy. Anesth Analg. 1986;65:185-187.

Serpell MG, Millar FA, Thomson MF. Comparison of lumbar plexus block versus conventional opioid analgesia after total knee replacement. Anaesthesia. 1991;46:275-277.

Wulf H, Schug SA, Allvin R. Postoperative patient management - how can we make progress?. Acute Pain. 1998;1:32-44.

Singelyn FJ, Deyaert M, Joris D. Effects of intravenous patient-controlled analgesia with morphine, continuous epidural analgesia, and continuous three-in-one block on postoperative pain and knee rehabilitation after unilateral total knee arthroplasty. Anesth Analg. 1998;87:88-92.

Catley DM, Thornton C, Jordan C. Pronounced, episodic oxygen desaturation in the postoperative period: its association with ventilatory pattern and analgesic regimen. Anesthesiology. 1985;63:20-28.

Bach S, Noreng MF, Tjellden NU. Phantom limb pain in amputees during the first 12 months following limb amputation, after preoperative lumbar epidural blockade. Pain. 1988;33:297-301.

Geier KO. Bloqueio do plexo braquial no trauma: analgesia regional prolongada por cateter axilar. Rev Bras Anestesiol. 1995;45:173-182.

Stevens DS, Dunn Jr WT. Acute Pain Management for the Trauma Patient. Acute Pain. 1992:412-421.

Tverskoy M, Oz Y, Isakson A et al. Preemptive effect of fentanyl and ketamine on postoperative pain and wound hyperalgesia. Anesth Analg. 1994;78:205-209.

Roytblat L, Korotkoruchko A, Katz J. Postoperative pain: the effect of low-dose ketamine in addition to general anesthesia. Anesth Analg. 1993;77:1161-1165.

Sakuragi T, Ishino H, Dan K. Bactericidal activity of preservative-free bupivacaine on microorganisms in the human skin flora. Acta Anaesthesiol Scand. 1998;42:1096-1099.

Sakuragi T, Ishino H, Dan K. Bactericidal activity of clinically used local anesthetics on staphylococcus aureus. Reg Anesth. 1996;21:239-242.

Elmas C, Atanassoff PG. Combined inguinal paravascular (3-in-1) and sciatic nerve blocks for lower limb surgery. Reg Anesth. 1993;18:88-92.

Covino BG, Vassalo HG. Anatomia do Nervo Periférico. Anestésicos Locais: Mecanismo de Ação e Uso Clínico. 1985.

Palve H, Kirvela O, Olin H. Maximum recommended doses of lignocaine are not toxic. B J Anaesth. 1995;74:704-705.

DiFazio CA, Woods AM. Fármacos Utilizados para el Bloqueo Nervioso. Tratamiento Práctico del Dolor. 1994:673-688.

Winnie AP, Ramamurthy S, Durrani Z. The inguinal paravascular technique of lumbar plexus anesthesia: the "3:1 block". Anesth Analg. 1973;52:989-996.

Dalens B, Tanguy A, Vanneuville G. Lumbar plexus block in children: a comparison of two procedures in 50 patients. Anesth Analg. 1988;67:750-758.

Capdevila X, Biboulet P, Bouregba M. Comparison of the three-in-one and fascia iliac compartment blocks in adults: clinical and radiographic analysis. Anesth Analg. 1998;86:1039-1044.

Hopkins PM, Ellis FR, Halsall PJ. Evaluation of local anaesthetic blockade of the lateral femoral cutaneous nerve. Anaesthesia. 1991;46:95-96.

Dalens B. Anesthésie Locorégionale de la Naissance à l'âge Adulte. 1993:325-352.

Tuominen M, Rosenberg PH, Kalso E. Blood levels of bupivacaine after single dose, supplementary dose and during continuous infusion in axillary plexus block. Acta Anaesthesiol Scand. 1983;27:303-306.

Vranken JH, van der Vegt MH, Zuurmond WW. Continuous brachial plexus block at the cervical level using a posterior approach in the management of neuropathic cancer pain. Reg Anesth Pain Med. 2001;26:572-575.

Aguilar JL, Domingo V, Samper D. Long-term brachial plexus anesthesia using a subcutaneous implantable injection system. Reg Anesth. 1995;20:242-245.

Goroszeniuk T, di Vadi PP. Repeated psoas compartment blocks for the management of long-standing hip pain. Reg Anesth Pain Med. 2001;26:376-378.

Cuvillon P, Ripart J, Lalourcey L. The continuous femoral nerve block catheter for postoperative analgesia: bacterial colonization, infectious rate and adverse effects. Anesth Analg. 2001;93:1045-1049.

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