Brazilian Journal of Anesthesiology
https://bjan-sba.org/article/doi/10.1590/S0034-70942003000400003
Brazilian Journal of Anesthesiology
Scientific Article

Comparação entre ventilação controlada a volume e a pressão no tratamento da hipoxemia no período pós-operatório de cirurgia de revascularização do miocárdio

Comparison between pressure controlled and controlled mandatory ventilation in the treatment of postoperative hypoxemia after myocardial revascularization

Fábio Bonini Castellana; Luiz Marcelo Sá Malbouisson; Maria José Carvalho Carmona; Célia Regina Lopes; José Otávio Costa Auler Júnior

Downloads: 1
Views: 831

Resumo

JUSTIFICATIVA E OBJETIVOS: Ventilação controlada à pressão tem sido utilizada como modalidade ventilatória de eleição em pacientes que desenvolvem hipoxemia importante no período pós-operatório de cirurgia de revascularização do miocárdio. Contudo não existem estudos mostrando que a ventilação controlada à pressão é mais efetiva na reversão da hipoxemia pós-operatória que ventilação controlada a volume. O objetivo deste estudo foi comparar os efeitos de ventilação controlada à pressão e ventilação controlada a volume sobre a oxigenação sistêmica em pacientes que desenvolvem hipoxemia caracterizada por uma relação PaO2/FiO2 menor que 200 no período pós-operatório imediato de cirurgia cardíaca. MÉTODO: Sessenta e um pacientes com relação PaO2/FiO2 menor que 200 foram alocados em um grupo submetido à ventilação controlada a pressão e outro a volume. O volume corrente, a freqüência respiratória, a relação inspiração/ expiração e a pressão positiva ao final da expiração foram as mesmas no dois grupos. Após a admissão na UTI e após períodos de 1 ou 2 horas de ventilação mecânica, a relação PaO2/FiO2 e o shunt pulmonar foram quantificados. RESULTADOS: Houve um aumento significativo na relação PaO2/FiO2 e uma diminuição significativa no shunt pulmonar após 1 ou 2 horas de ventilação mecânica; contudo não foram observadas diferenças entre as modalidades ventilatórias. CONCLUSÕES: As modalidades ventilatórias controladas a volume e pressão foram igualmente eficientes no tratamento da hipoxemia observada em pacientes no pós-operatório imediato de cirurgia de revascularização do miocárdio, mostrando que o padrão de administração do fluxo inspiratório é pouco relevante para o tratamento da hipoxemia pós-operatória.

Palavras-chave

CIRURGIA, CIRURGIA, COMPLICAÇÕES, VENTILAÇÃO

Abstract

BACKGROUND AND OBJECTIVES: Pressure controlled ventilation (PCV) has been used as the ventilation mode of choice in coronary artery bypass graft surgery patients who develop severe hypoxemia in the immediate postoperative period. However, there are no evidences showing that pressure controlled ventilation is more effective in reversing postoperative hypoxemia than controlled mandatory ventilation (CMV). This study aimed at comparing the effects of both ventilation modes on systemic oxygenation in cardiac surgery patients who develop hypoxemia characterized by PaO2/FiO2 ratio lower than 200 in the immediate postoperative period. METHODS: Participated in this study 61 consecutive patients with PaO2/FiO2 ratio lower than 200 who were randomly allocated in two groups according to the ventilatory mode (CMV and PCV). Tidal volume, respiratory rate, inspiration/expiration ratio and positive end-expiratory pressure were kept constant throughout the study in both groups. PaO2/FiO2 ratio and pulmonary shunt were obtained 1 or 2 hours after ICU admission. RESULTS: A significant increase in PaO2/FiO2 ratio and a decrease in pulmonary shunt were observed in both groups one or two hours after mechanical ventilation. However, no differences were observed between both ventilatory modes. CONCLUSIONS: Both ventilatory modes were equally effective in reversing hypoxemia observed in the immediate cardiac surgery postoperative period. Results show that inspiratory flow patterns are not relevant in the treatment of post cardiac surgery hypoxemia.

Keywords

COMPLICATIONS, SURGERY, SURGERY, VENTILATION

References

Auler Jr JOC, Carmona MJ, Barbas CV. The effects of positive end-expiratory pressure on respiratory system mechanics and hemodynamics in postoperative cardiac surgery patients. Br J Med Biol Res. 2000;33:31-42.

Rouby JJ. Histology and microbiology of ventilator-associated pneumonia’s. Semin Respir Infect. 1996;11:54-61.

Artigas AT, Bello Dronda S, Chacon Valles E. Risk factors for nosocomial pneumonia in critically ill trauma patients. Crit Care Med. 2001;29:304-309.

Rappaport SH, Shpiner R, Yoshihara G. Randomized, prospective trial of pressure-limited versus volume-controlled ventilation in severe respiratory failure. Crit Care Med. 1994;22:22-32.

Esteban A, Alia I, Gordo F. Prospective randomized trial comparing pressure-controlled ventilation and volume-controlled ventilation in ARDS: For the Spanish Lung Failure Collaborative Group. Chest. 2000;117:1690-1696.

Munoz J, Guerrero JE, Escalante JL. Pressure-controlled ventilation versus controlled mechanical ventilation with decelerating inspiratory flow. Crit Care Med. 1993;21:1143-1148.

Dreyfuss D, Soler P, Basset G. High inflation pressure pulmonary edema: Respective effects of high airway pressure, high tidal volume, and positive end-expiratory pressure. Am Rev Resp Dis. 1988;137:1159-1164.

Dreyfuss D, Saumon G. Overexpansion pulmonary edema. J Appl Physiol. 1991;71:777-778.

Dreyfuss D, Saumon G. Synergistic interaction between alveolar flooding and distention during mechanical ventilation. Am J Respir Crit Care Med. 1996;153(^sSuppl):A12.

Dreyfuss D, Saumon G. Ventilator-induced lung injury: lessons from experimental studies. Am J Respir Crit Care Med. 1998;157:294-323.

Amato MB, Barbas CS, Medeiros DM. Effect of a protective-ventilation strategy on mortality in the acute respiratory distress syndrome. N Engl J Med. 1998;338:347-354.

Beck K, Malbouisson LMS, Hueb AC. Tempo para extubação no pós-operatório de cirurgia cardíaca: correlação entre tempo para extubação e duração de circulação extracorpórea, hidratação per-operatória e relação PaO2/FiO2. Rev Bras Anestesiol. 1998;48:CBA.

Markowicz P, Wolff M, Djedaini K. Multicenter prospective study of ventilator-associated pneumonia during acute respiratory distress syndrome. Incidence, prognosis, and risk factors. ARDS Study Group. Am J Respir Crit Care Med. 2000;161:1942-1948.

Froese AB, Bryan AC. Effects of anesthesia and paralysis on diaphragmatic mechanics in man. Anesthesiology. 1974;41:242-254.

Malbouisson LM, Busch CJ, Puybasset L. Role of the heart in the loss of aeration characterizing lower lobes in acute respiratory distress syndrome. CT Scan ARDS Study Group. Am J Respir Crit Care Med. 2000;161:2005-2012.

Tenling A, Hachenberg T, Tyden H. Atelectasis and gas exchange after cardiac surgery. Anesthesiology. 1998;89:371-378.

Guest Jr Jl, Sekulic SM, Yeh TJ. Role of atelectasis in surfactant abnormalities following extracorporeal circulation. A clinical and experimental study. Circulation. 1966;33:165-170.

Pizov R, Weiss YG, Oppenheim-Eden A. High oxygen concentration exacerbates cardiopulmonary bypass-induced lung injury. J Cardiothorac Vasc Anesth. 2000;14:519-523.

Pelosi P, D’andrea L, Vitale G. Vertical gradient of regional lung inflation in adult respiratory distress syndrome. Am J Respir Crit Care Med. 1994;149:8-13.

Magnusson L, Zemgulis V, Wicky S. Atelectasis is a major cause of hypoxemia and shunt after cardiopulmonary bypass: an experimental study. Anesthesiology. 1997;87:1153-1163.

Auler Jr JOC, Zin WA, Caldeira MP. Pre and postoperative inspiratory mechanics in ischemic and valvular heart disease. Chest. 1987;92:984-990.

Ranieri VM, Vitale N, Grasso S. Time-course of impairment of respiratory mechanics after cardiac surgery and cardiopulmonary bypass. Crit Care Med. 1999;27:1454-1460.

Hachenberg T, Lundquist H, Tokics L. Analysis of lung density by computed tomography before and during general anaesthesia. Acta Anaesthesiol Scand. 1993;37:549-555.

Malbouisson LM, Muller JC, Constantin JM. Computed tomography assessment of positive end-expiratory pressure-induced alveolar recruitment in patients with acute respiratory distress syndrome. Am J Respir Crit Care Med. 2001;163:1444-1450.

Auler Jr JOC, Carmona MJC, Silva MH. Haemodynamic effects of pressure-controlled ventilation versus volume-controlled ventilation in patients submitted to cardiac surgery. Clin Intensive Care. 1995;6:100-106.

5ddd314b0e882572741da3e9 rba Articles
Links & Downloads

Braz J Anesthesiol

Share this page
Page Sections