1. Rocha KO, Santos ERFA, Pombeiro MM, et al. Intranasal dexmedetomidine for procedural sedation in children: a systematic review and meta-analysis. Braz J Anesthesiol. 2026;76:844717.

2. Li BL, Zhang N, Huang JX, et al. A comparison of intranasal dexmedetomidine for sedation in children administered either by atomiser or by drops. Anaesthesia. 2016;71:522−8.

3. Xie Z, Shen W, Lin J, et al. Sedation effects of intranasal dexmedetomidine delivered as sprays versus drops on pediatric response to venous cannulation. Am J Emerg Med. 2017;35:1210−4.

4. Li A, Yuen VM, Goulay-Dufay S, et al. Pharmacokinetic and pharmacodynamic study of intranasal and intravenous dexmedetomidine. Br J Anaesth. 2018;120:960−8.

5. Wolfe TR, Braude DA. Intranasal medication delivery for children: a brief review and update. Pediatrics. 2010;126:532−7.