Brazilian Journal of Anesthesiology
https://bjan-sba.org/article/doi/10.1016/j.bjane.2025.844643
Brazilian Journal of Anesthesiology
Original Investigation

Comparison of pericapsular nerve group block and anterior quadratus lumborum block for hip fracture surgery: a randomized clinical trial

Comparação entre o bloqueio do grupo de nervos pericapsulares e o bloqueio quadrado lombar anterior para cirurgia de fratura de quadril: ensaio clínico randomizado

Mustafa Aslan, Alper Kilicaslan, Funda Gök, Ahmet Fevzi Kekec, Tahsin Sami Colak

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Abstract

Objective

This study compared the Pericapsular Nerve Group (PENG) block combined with the Lateral Femoral Cutaneous Nerve (LFCN) block to the anterior Quadratus Lumborum Block (QLB) in patients undergoing Total Hip Arthroplasty (THA).

Methods

In this prospective, double-blind trial, 80 adults scheduled for THA under spinal anesthesia were randomized to receive either an anterior QLB (n = 40) with 30 mL of 0.25% bupivacaine or a combined PENG + LFCN block (n = 40) using 25 mL of 0.25% bupivacaine for PENG and 5 mL for LFCN. The primary outcome was cumulative 24 hour postoperative intravenous morphine consumption. Secondary outcomes included pain scores, quadriceps strength, patient satisfaction and side effects.

Results

No significant differences were observed between the groups in morphine consumption or pain scores during the first 12 hours (p > 0.05). At 24 hours, the PENG + LFCN group demonstrated significantly lower morphine consumption (p = 0.027) and resting VAS scores (p < 0.001). Quadriceps weakness occurred in 15% (6/40) of anterior QLB patients at 6 hours (p = 0.026), whereas no weakness was observed in the PENG + LFCN group within 24 hours. Patient satisfaction and the incidence of complications were comparable between the groups.

Conclusion

Both anterior QLB and PENG + LFCN blocks provide effective analgesia for up to 12 hours post-THA. However, the PENG + LFCN combination offers prolonged analgesia, reduced opioid requirements and better preservation of quadriceps strength.

Keywords

Anesthesia; Arthroplasty; Hip fractures; Nerve block; Postoperative pain

Resumo

Introdução

Este estudo comparou o bloqueio do Grupo de Nervos Pericapsulares (PENG) combinado com o bloqueio do Nervo Cutâneo Femoral Lateral (LFCN) ao bloqueio anterior do Bloqueio do Quadrado Lombar (QLB) em pacientes submetidos à Artroplastia Total de Quadril (THA).

Métodos

Neste ensaio prospectivo, duplo-cego, 80 adultos programados para THA sob anestesia raquidiana foram randomizados para receber bloqueio anterior de QLB (n = 40) com 30 mL de bupivacaína 0,25% ou bloqueio combinado PENG + LFCN (n = 40) utilizando 25 mL de bupivacaína 0,25% para PENG e 5 mL para LFCN. O desfecho primário foi o consumo acumulado de morfina intravenosa nas primeiras 24 horas pós-operatórias. Desfechos secundários incluíram escores de dor, força do quadríceps, satisfação do paciente e efeitos colaterais.

Resultados

Não foram observadas diferenças significativas entre os grupos no consumo de morfina ou escores de dor durante as primeiras 12 horas (p > 0,05). Com 24 horas, o grupo PENG + LFCN apresentou consumo significativamente menor de morfina (p = 0,027) e escores de VAS em repouso mais baixos (p < 0,001). Fraqueza do quadríceps ocorreu em 15% (6/40) dos pacientes do bloqueio anterior de QLB às 6 horas (p = 0,026), enquanto nenhum caso de fraqueza foi observado no grupo PENG + LFCN nas 24 horas avaliadas. A satisfação dos pacientes e a incidência de complicações foram comparáveis entre os grupos.

Conclusão

Tanto o bloqueio anterior de QLB quanto o bloqueio combinado PENG + LFCN proporcionam analgesia eficaz por até 12 horas após a THA. Entretanto, a combinação PENG + LFCN oferece analgesia prolongada, redução na necessidade de opioides e melhor preservação da força do quadríceps.

Palavras-chave

Anestesia; Artroplastia; Fraturas de quadril; Bloqueio nervoso; Dor pós-operatória

References

1. Ryan SP, Stambough JB, Huddleston JI, Levine BR. Highlights of the 2023 American joint replacement registry annual report. Arthroplast Today. 2024;26:101325.

2. Hannon CP, Keating TC, Lange JK, Ricciardi BF, Waddell BS, Della Valle CJ. Anesthesia and analgesia practices in total joint arthroplasty: a survey of the American Association of Hip and Knee Surgeons membership. J Arthroplasty. 2019;34:2872−7.

3. Karlsen APH, Geisler A, Petersen PL, Mathiesen O, Dahl JB. Postoperative pain treatment after total hip arthroplasty: a systematic review. Pain. 2015;156:8−30.

4. Chou R, Gordon DB, de Leon-Casasola OA, et al. Management of Postoperative Pain: a clinical practice guideline from the American pain society, the American Society of Regional Anesthesia and Pain Medicine, and the American Society of Anesthesiologists’ committee on regional anesthesia, executive committee, and administrative council. J Pain. 2016;17:131−57.

5. Bugada D, Bellini V, Lorini LF, Mariano ER. Update on selective regional analgesia for hip surgery patients. Anesthesiol Clin. 2018;36:403−15.

6. Kukreja P, MacBeth L, Sturdivant A, et al. Anterior quadratus lumborum block analgesia for total hip arthroplasty: a randomized, controlled study. Reg Anesth Pain Med. 2019;44:1075−9.

7. Giron-Arango L, Peng PW, Chin KJ, Brull R, Perlas A. Pericapsu- lar nerve group (PENG) block for hip fracture. Reg Anesth Pain Med. 2018;43:859−63.

8. Wang N, Ruan B, Wang M, et al. Ultrasound-guided oblique sagittal anterior quadratus lumborum block in total hip arthroplasty: A randomized controlled trial. Pain Physician. 2022;25:E609−17.

9. Abduallah MA, Ahmed SA, Abdelghany MS. The effect of postoperative ultrasound-guided transmuscular quadratus lumborum block on post-operative analgesia after hip arthroplasty in elderly patients: a randomised controlled double-blind study. Indian J Anaesth. 2020;64:887−93.

10. Hu J, Wang Q, Zeng Y, Xu M, Gong J, Yang J. The impact of ultrasound-guided transmuscular quadratus lumborum block combined with local infiltration analgesia for arthroplasty on postoperative pain relief. J Clin Anesth. 2021;73:110372.

11. Short AJ, Barnett JJG, Gofeld M, et al. Anatomic study of innervation of the anterior hip capsule: implication for image-guided intervention. Reg Anesth Pain Med. 2018;43:186−92.

12. Jadon A, Sinha N, Chakraborty S, Ahmad A. An out-of-plane approach for pericapsular nerve group block: a case series. Bali J Anesth. 2020;4:67−70.

13. Zheng J, Pan D, Zheng B, Ruan X. Preoperative pericapsular nerve group (PENG) block for total hip arthroplasty: a randomized, placebo-controlled trial. Reg Anesth Pain Med. 2022;47: 155−60.

14. Jadon A, Srivastawa S, Bakshi A, Sahoo RK, Singh BK, Sinha N. Does adding lateral femoral cutaneous nerve block improves the analgesia of pericapsular nerve group block in the fractured hip surgeries? Braz J Anesthesiol. 2022;72:836−8.

15. Roy R, Agarwal G, Pradhan C, Kuanar D. Total postoperative analgesia for hip surgeries, PENG block with LFCN block. Reg Anesth Pain Med. 2019;44:684.

16. Et T, Korkusuz M. Comparison of the pericapsular nerve group block with the intra-articular and quadratus lumborum blocks in primary total hip arthroplasty: a randomized controlled trial. Korean J Anesth. 2023;76:575.

17. Abdelsalam TA, Hossam-Eldein N, Tarabeah GA, Gouda SEK. Ultrasound-guided pericapsular nerve group block and anterior quadratus lumborum block for analgesia in hip arthroplasty: a prospective randomized comparative study. Res Opinion Anesth Intensive Care. 2024;11:193−200.

18. Hay E, Kelly T, Wolf BJ, et al. Comparison of pericapsular nerve group and lateral quadratus lumborum blocks on cumulative opioid consumption after primary total hip arthroplasty: a randomized controlled trial. Reg Anesth Pain Med. 2024;rapm2024:105875. https://doi.org/10.1136/rapm-2024-105875. Online ahead of print.

19. Wang QR, Ma T, Hu J, Yang J, Kang PD. Comparison between ultrasound-guided pericapsular nerve group block and anterior quadratus lumborum block for total hip arthroplasty: a doubleblind, randomized controlled trial. Eur Rev Med Pharmacol Sci. 2023;27:7523−32.

20. Braun AS, Lever JEP, Kalagara H, et al. Comparison of Pericapsular Nerve Group (PENG) Block Versus Quadratus Lumborum (QL) Block for Analgesia After Primary Total Hip Arthroplasty Under Spinal Anesthesia: A Retrospective Study. Cureus. 2023;15:e50119.

21. Clark BC, Manini TM, Wages NP, Simon JE, Clark LA. Voluntary vs electrically stimulated activation in age-related muscle weakness. JAMA Network Open. 2019;2:e1912052.

22. He J, Zhang L, He WY, et al. Ultrasound-guided transmuscular quadratus lumborum block reduces postoperative pain intensity in patients undergoing total hip arthroplasty: a randomized, double-blind, placebo-controlled trial. Pain Res Manag. 2020; 2020:1035182.

23. Nassar H, Hasanin A, Sewilam M, et al. Transmuscular quadratus lumborum block versus suprainguinal fascia iliaca block for hip arthroplasty: a randomized, controlled pilot study. Local Reg Anesth. 2021;14:67−74.

24. Chung CJ, Eom DW, Lee TY, Park SY. Reduced Opioid Consumption with Pericapsular Nerve Group Block for Hip Surgery: A Randomized, Double-Blind, Placebo-Controlled Trial. Pain Res Manag. 2022;2022:6022380.

25. Mosaffa F, Taheri M, Rasi AM, Samadpour H, Memary E, Mirkheshti A. Comparison of pericapsular nerve group (PENG) block with fascia iliaca compartment block (FICB) for pain control in hip fractures: a double-blind prospective randomized controlled clinical trial. Orthop Traumatol Surg Res. 2022;108:103135.

26. Huda AU, Ghafoor H. The use of pericapsular nerve group (PENG) block in hip surgeries is associated with a reduction in opioid consumption, less motor block, and better patient satisfaction: a meta-analysis. Cureus. 2022;14:e28872.

27. Aliste J, Layera S, Bravo D, et al. Randomized comparison between pericapsular nerve group (PENG) block and suprainguinal fascia iliaca block for total hip arthroplasty. Reg Anesth Pain Med. 2021;46:874−8.

28. Giron-Arango L, Peng P. Pericapsular nerve group (PENG) block: what have we learned in the last 5 years? Reg Anesth Pain Med. 2024;9:105427.

29. Adhikary SD, El‑Boghdadly K, Nasralah Z, Sarwani N, Nixon AM, Chin KJ. A radiologic and anatomic assessment of injectate spread following transmuscular quadratus lumborum block in cadavers. Anaesthesia. 2017;72:73‑9.

30. Dam M, Moriggl B, Hansen CK, Hoermann R, Bendtsen TF, Børglum J. The pathway of injectate spread with the transmuscular quadratus lumborum block: A cadaver study. Anesth Analg. 2017;125:303‑12.


Submitted date:
02/10/2025

Accepted date:
05/03/2025

68c977eda953956095382b25 rba Articles
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