Brazilian Journal of Anesthesiology
https://bjan-sba.org/article/doi/10.1016/j.bjane.2023.03.002
Brazilian Journal of Anesthesiology
Short Communications

Transcranial Direct Current Stimulation (tDCS) antinociceptive effect is not altered by isoflurane anesthesia in neuropathic pain rats

Lisiane Santos da Silva, Roberta Ströher Toledo, Dirson João Stein, Josimar Macedo de Castro, Wolnei Caumo, Iraci L.S. Torres

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Keywords

Neuropathic pain, Isoflurane, tDCS, von Frey Test, IL-10

References

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4. Adachi LNS, Quevedo AS, Souza A, Scarabelot VL, Rozisky JR, de Oliveira C, et al. Exogenously induced brain activation regulates neuronal activity by top‑down modulation: conceptualized model for electrical brain stimulation. Exp Brain Res. 2015;233:1377−89.

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6. Hua T, Chen B, Lu D, Sakurai K, Zhao S, Han BX, et al. General Anesthetics Activate a Potent Central Pain-Suppression Circuit in the Amygdala. Nat Neurosci. 2020;23:854−68.

7. Lopes BC, Medeiros LF, Souza VS, Cioato SG, Medeiros HR, Regner GG, et al. Transcranial direct current stimulation combined with exercise modulates the inflammatory profile and hyperalgesic response in rats subjected to a neuropathic pain model: Long-term effects. Brain Stimul. 2020;13:774−82.

8. Bennett GJ, Xie YK. A Peripheral Mononeuropathy in Rat That Produces Disorders of Pain Sensation Like Those Seen in Man. Pain. 1988;34:87−107.

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10. Okamoto K, Martin DP, Schmelzer JD, Mitsui T, Low PA. Pro- and anti-inflammatory cytokine gene expression in rat sciatic nerve chronic constriction injury model of neuropathic pain. Exp Neurol. 2001;169:386−91.

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Braz J Anesthesiol

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