Brazilian Journal of Anesthesiology
https://bjan-sba.org/article/doi/10.1016/j.bjane.2021.07.003
Brazilian Journal of Anesthesiology
Clinical Research

Derivation and validation of a national multicenter mortality risk stratification model – the ExCare model: a study protocol

Sávio Cavalcante Passos; Adriene Stahlschmidt; João Blanco; Mariana Lunardi Spader; Rodrigo Borges Brandão; Stela Maris de Jezus Castro; Claudia de Souza Gutierrez; Paulo Corrêa da Silva Neto; Luciana Paula Cadore Stefani

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Abstract

Introduction
Surgical care is essential for proper management of various diseases. However, it can result in unfavorable outcomes. In order to identify patients at higher risk of complications, several risk stratification models have been developed. Ideally, these tools should be simple, reproducible, accurate, and externally validated. Unfortunately, none of the best-known risk stratification instruments have been validated in Brazil. In this sense, the Ex-Care model was developed by retrospective data analysis of surgical patients in a major Brazilian university hospital. It consists of four independent predictors easily collected in the preoperative evaluation, showing high accuracy in predicting death within 30 days after surgery.

Objectives
To update and validate a Brazilian national-based model of postoperative death probability within 30 days based on the Ex-Care model. Also, to develop an application for smartphones that allows preoperative risk stratification by Ex-Care model.

Methods
Ten participating centers will collect retrospective data from digital databases. Variables age, American Society of Anesthesiology (ASA) physical status, surgical severity (major or non-major) and nature (elective or urgent) will be evaluated as predictors for in-hospital mortality within 30 postoperative days, considered the primary outcome.

Expected results
We believe that the Ex-Care model will present discriminative capacity similar to other classically used scores validated for surgical mortality prediction. Furthermore, the mobile application to be developed will provide a practical and easy-to-use tool to the professionals enrolled in perioperative care.

Keywords

Surgical procedures;  Risk assessment;  Hospital mortality;  Validation studies;  Mobile health application
6107f670a9539540c447fb23 rba Articles
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Braz J Anesthesiol

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