Brazilian Journal of Anesthesiology
https://bjan-sba.org/article/doi/10.1016/j.bjane.2021.02.050
Brazilian Journal of Anesthesiology
Case Report

Evaluation of the Density Spectral Array in the Wada test: report of six cases

Pacreu Susana, Esther Vilà, Luis Moltó, Rodrigo Rocamora, Juan Luis Fernández-Candil

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Abstract

Wada test is an invasive procedure used in the preoperative evaluation for epilepsy surgery to determine language lateralization, post-operative risk of amnesia syndrome, and to assess the risk of memory deficits. It involves injection of amobarbital into internal carotid artery of the affected hemisphere followed by the healthy hemisphere to shut down brain function. We performed an observational study evaluating the density spectral array (DSA) of the bilateral bispectral index VISTATM Monitoring System (BVMS) in 6 patients with drug-resistant epilepsy undergoing Wada test. DSA revealed the presence of bifrontal alpha waves in absence of loss of consciousness in all patients.

Keywords

Wada test,  Epilepsy,  Amobarbital,  Alpha waves,  Density spectral array,  Consciousness, loss of

References

1 B. Abou-Khalil An update on determination of language dominance in screening for epilepsy surgery: the Wada test and newer non-invasive alternatives Epilepsia, 48 (2007), pp. 442-455

2 M. Zijlmans, C.J. Huibers, G.J. Huiskamp, et al. The contribution of posterior circulation to memory function during the intracarotid amobarbital procedure J Neurol, 259 (2012), pp. 1632-1638

3 P.L. Purdon, A. Sampson, K.J. Pavone, et al. Clinical Electroencephalography for anesthesiologists Anesthesiology, 123 (2015), pp. 1-24

4 P. Purdon, E. Pierce, E. Mukamel, et al. Electroencephalogram signatures of loss and recovery of consciousness from propofol Proc Natl Acad Sci U S A, 110 (2013), pp. E1142-51

5 W. Löscher, M.A. Rogawski How theories evolved concerning the mechanism of action of barbiturates Epilepsia, 53 (2012), pp. 12-25

6 S. Blain-Moraes, V. Tarnal, G. Vanini, et al. Neurophysiological correlates of sevoflurane-induced unconsciousness Anesthesiology, 122 (2015), pp. 307-316

7 L. Douw, J.C. Baayen, M. Klein, et al. Functional connectivity in the brain before and during intra-arterial amobarbital injection (Wada test) Neuroimage, 46 (2009), pp. 584-588

8 S. Bookheimer, L.M. Schrader, R. Raush, et al. Reduced anesthetization during the intracarotid amobarbital (Wada) test in patients taking carbonic anhydrase-inhibiting medications Epilepsia, 46 (2005), pp. 236-243
 

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