Brazilian Journal of Anesthesiology
Brazilian Journal of Anesthesiology
Original Investigation

Risk factors for failure of subclavian vein catheterization: a retrospective observational study

Fatores de risco para falha da cateterização da veia subclávia: um estudo observacional retrospectivo

Ren-Xiong Chen, Hong-Zhi Wang, Yong Yang, Xiao-Jie Chen

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Background and objectives
The aim of this study was to analyze risk factors for failure of subclavian vein catheterization.

A retrospective analysis of 1562 patients who underwent subclavian vein puncture performed by the same experienced operator at Peking University Cancer Hospital from January 1, 2016 to January 1, 2019 was conducted. The success or failure of subclavian vein catheterization was registered in all cases. Various patient characteristics, including age, gender, body mass index (BMI), preoperative hemoglobin, preoperative hematocrit, preoperative mean corpuscular hemoglobin concentration (MCHC), preoperative albumin, preoperative serum creatinine, puncture needles from different manufacturers and previous history of subclavian vein catheterization were assessed via univariate and multivariate analyses.

For the included patients, landmark-guided subclavian vein puncture was successful in 1476 cases and unsuccessful in 86 cases (success rate of 94.5%). Successful subclavian vein catheterization was achieved via right and left subclavian vein puncture in 1392 and 84 cases, respectively. In univariate analyses, age and preoperative hemoglobin were associated with failure of subclavian vein catheterization. In a multivariate analysis, aged more than 60 years was a risk factor while the central venous access with Certofix® was associated with an increased rate of success (p-values of 0.001 and 0.015, respectively).

This study has demonstrated that patient aged more than 60 years was a risk factor for failure of subclavian vein catheterization while the central venous access with Certofix® was associated with an increased rate of success.


Subclavian vein catheterization;  Central venous access;  Central venous catheter;  Catheter-related complications


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