Brazilian Journal of Anesthesiology
https://bjan-sba.org/article/doi/10.1016/j.bjane.2021.02.015
Brazilian Journal of Anesthesiology
Clinical Research

Effect of intravenous lidocaine on short-term pain after hysteroscopy: a randomized clinical trial

Xuan Peng, Yuzi Zhao, Yeda Xiao, Liying Zhan, Huaxin Wang

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Abstract

Background
The role of intravenous lidocaine infusion in endoscopic surgery has been previously evaluated for pain relief and recovery. Recently, it has been shown to reduce postoperative pain and opioid in patients undergoing endoscopic submucosal dissection. Similar to endoscopic submucosal dissection, operative hysteroscopy is also an endoscopic surgical procedure within natural lumens. The present study was a randomized clinical trial in which we evaluated whether intravenous lidocaine infusion would reduce postoperative pain in patients undergoing hysteroscopic surgery.

Objective
To evaluate whether intravenous lidocaine infusion could reduce postoperative pain in patients undergoing operative hysteroscopy.

Methods
Eighty-five patients scheduled to undergo elective hysteroscopy were randomized to receive either an intravenous bolus of lidocaine 1.5 mg.kg-1 over 3-minutes, followed by continuous infusion at a rate of 2 mg.kg-1. h-1 during surgery, or 0.9% normal saline solution at the same rate. The primary outcome was to evaluate postoperative pain by Visual Analog Scale (VAS). Secondary outcomes included remifentanil and propofol consumption.

Results
In the lidocaine group, the VAS was significantly lower at 0.5 h (p =  0.008) and 4h (p =  0.020). Patients in the lidocaine group required less remifentanil than patients in the control group (p <  0.001). However, there was no difference between the two groups in the propofol consumption. The incidence of throat pain was significantly lower in the lidocaine group (p =  0.019). No adverse events associated with lidocaine infusion were discovered.

Conclusion
Intravenous lidocaine infusion as an adjuvant reduces short-term postoperative pain in patients undergoing operative hysteroscopy.

Keywords

Anesthesia;  Hysteroscopy;  Lidocaine;  Postoperative pain;  Propofol
60268afa0e8825c2664de1ce rba Articles
Links & Downloads

Rev. Bras. Anestesiol.

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