1 H.I. Kemps, T.M. Cook, M. Thomas, N.J.N. Harper UK anaesthetists’ perspectives and experiences of severe perioperative anaphylaxis: NAP6 baseline survey Br J Anaesth., 119 (2017), pp. 132-139

2 P.M. Mertes, G.W. Volcheck, L.H. Garvey, et al. Epidemiology of perioperative anaphylaxis Presse Med., 45 (2016), pp. 758-767

3 P.M. Mertes, M. Lambert, R.M. Guéabt-Rodriguez, et al. Perioperative anaphylaxis Immunol Allergy Clin N Am., 29 (2009), pp. 429-451

4 L.S. Garro, M.V. Aun, I.S. Soares, et al. Specific questionnaire detects a high incidence of intra-operative hypersensitivity reactions Clinics., 113 (2018), pp. 1202-1212

5 P. Dewachter, P. Kopac, J.J. Laguna, et al. Anaesthetic management of patients with pre-existing allergic conditions: a narrative review Br J Anaesth., 123 (2019), pp. e50-e64

6 G.W. Volcheck, D.L. Hepner Identification and management of perioperative anaphylaxis J Allergy Clin Immunol Pract, 7 (2019), pp. 2134-2142

7 L.H. Garvey, P. Dewachter, D.L. Hepner, et al. Management of suspected immediate perioperative allergic reactions: an international overview and consensus recommendations Br J Anaesth., 123 (2019), pp. e50-e64

8 V. Sabato, P. Platt, T. Garcez, P. Cooke Suspected perioperative allergic reactions: nomenclature and terminology Br J Anaesth., 123 (2019), pp. e13-e15

9 L.K. Tanno, M.J. Torres, M. Castells, P. Demoly, on behalf of the Joint Allergy Academies What can we learn in drug allergy management from World Health Organization's international classifications? Allergy., 73 (2018), pp. 987-992

10 L.K. Tanno, F.E. Simons, I. Annesi-Maesano, et al. Fatal anaphylaxis registries data support changes in the WHO anaphylaxis mortality coding rules Orphanet J Rare Dis., 12 (2017), p. 8

11 S.G.O. Johansson, T. Bieber, R. Dahl, et al. Revised nomenclature for allergy for global use: Report of the Nomenclature Review Committee of the World Allergy Organization, October 2003 J Allergy Clin Immunol., 113 (2004), pp. 832-836

12 D.G. Ebo, R.C. Clarke, P.M. Mertes, P.R. Platt, V. Sabato, P.H.M. Sadleir Molecular mechanisms and pathophysiology of perioperative hypersensitivity and anaphylaxis: a narrative review Br J Anaesth., 123 (2019), pp. e38-e49

13 J. Ring, K. Messmer Incidence and severity of anaphylactoid reactions to colloid volume substitutes Lancet., 1 (1977), pp. 466-469

14 Société Française d’Anesthesie et de Réanimation Socété Française d’Allergologie. Reducing the risk of the anaphylaxis during anaesthesia. Short text Ann Fr Anesth Reanim., 30 (2011), pp. 212-222

15 P.M. Mertes, J.M. Malinovsky, L. Jouffroy Working Group of the SFAR and SFA, Aberer W, Tereehorst I, et al. Reducing the risk of anaphylaxis during anesthesia: 2011 update guidelines for clinical practice J Investig Allergol Clin Immunol., 21 (2011), pp. 442-453

16 P.M. Hopkins, P.J. Cooke, R.C. Clarke, et al. Consensus clinical scoring for suspected perioperative immediate hypersensitivity reactions Br J Anaesth., 123 (2019), pp. e29-e37

17 Joint Task Force on Practice Parameters, American Academy of Allergy, Asthma and Immunology, American College of Allergy, Asthma and Immunology, Joint Council of Allergy, Asthma and Immunology The diagnosis and management of anaphylaxis: an updated practical parameter J Allergy Clin immunol., 115 (3 Suppl 2) (2005), pp. S483-S523

18 P. Dewachter, C. Mouton-Faivre, C.W. Emala Anaphylaxis and anesthesia: controversies and new insights Anesthesiology., 111 (2009), pp. 1141-1150

19 S.G.A. Brown Cardiovascular aspects of anaphylaxis: implications for treatment and diagnosis Curr Opin Allerg Clin Immunol., 5 (2005), pp. 359-364

20 R. Clarke, P. Sadleir, A.W. Van Niekerk, P. Platt Quantification of volume loss and haemodynamic changes of Gelofusine-induced anaphylaxis during cardiopulmonar by-pass Anaesth Intensive Care., 39 (2011), pp. 492-495

21 N.G. Kounis Kounis syndrome (allergic angina and allergic myocardial infarction): a natural paradigma? Int J Cardiol., 110 (2006), pp. 7-14

22 J.A. Franco Hernandez, A. García Hernandez, D. Lahoz Rodríguez Kounis syndrome secondary to an allergic reaction to metamizole Rev Esp Anestesiol Reanim., 59 (2012), pp. 217-219

23 A. Gouel-Chéron, C. Neukirch, B. Aubier, et al. Anaphylactic bronchospasm during general anesthesia is not related to asthma Allergy., 70 (2015), pp. 453-456

24 F.E. Simmons, L.R. Ardusso, M.B. Bilò, et al. World Allergy Organization anaphylaxis guidelines: summary J Allergy Clin Immunol., 127 (2011), pp. 587-593

25 M. Kroigaard, L.H. Garvey, L. Gillberg, et al. Scandinavian Clinical Practice Guidelines on the diagnosis, management and follow-up of anaphylaxis during anaesthesia Acta Anesthesiol Scand., 51 (2007), pp. 655-670

26 H. Kolawole, S.D. Marshall, H. Crilly, R. Kerridge, S. Roessler Australian and New Zealand Anaesthetic Allergy Group/Australian and New Zealand College of Anaesthetists Perioperative Anaphylaxis Management Guidelines Anaesth Intensive Care., 45 (2017), pp. 151-158

27 P. Dewachter, C. Mouton-Faivre, D.L. Hepner Perioperative Anaphylaxis: what should be known? Curr Allergy Asthma Rep., 15 (2015), p. 21

28 M.A.C. Spindola, J. da Silva Anafilaxia e anestesia. In: Sociedade Brasileira de Anestesiologia. Nunes RR, Bagatini A, Duarte LTD (org). PROANESTESIA Programa de Atualização em Anestesiologia: Ciclo 1 Artmed Panamericana, Porto Alegre (2018) p9-49 (Sistema de Educação Continuada à Distância, vol. 3)

29 P.W. Ewan, P. Dugué, R. Mirakian, T.A. Dixon, J.N. Harper, S.M. Nasser BSACI guidelines for the investigation of suspected anaphylaxis during general anesthesia Clin Exp Allergy., 40 (2009), pp. 15-31

30 J.J. Laguna, J. Archilla, I. Doña, M. Corominas, G. Gastaminza, C. Mayorga, et al. Practical guidelines for perioperative hypersensitivity reactions J Investig Allergol Immunol., 28 (2018), pp. 216-232

31 G.W. Volcheck, P.M. Mertes Local and general anesthetics immediate hypersensitivity reactions Immunol Allergy Clin N Am., 34 (2014), pp. 525-546

32 S.F. Kemp, R.F. Lockey, F.E. Simmons World allergy Organization ad hoc Committee on Epinephrine in Anaphylaxis. Epinephrine: the drug of choice for anaphylaxis: a statement of the World Allergy Organization Allergy., 63 (2008), pp. 1061-1070

33 F.E. Simmons Anaphylaxis: recent advances in assessment and treatment J Allergy Clin Immunol., 124 (2009), pp. 625-636

34 U.R. Mueller Cardiovascular disease and anaphylaxis Curr Opin Allergy. (2007), pp. 337-341

35 P. Lieberman, R.A. Nicklas, C. Randolph, et al. Anaphylaxis – a practice parameter update 2015 Ann Allergy Asthma Immunol., 115 (2015), pp. 341-384

36 R.S. Pumphrey Lessons for management from a study of fatal reactions Clin Exp Allergy., 30 (2000), pp. 1114-1150

37 R.L. Campbell, F. Bellolio, B.D. Knutson, et al. Higher risk of cardiovascular complications and overdose after administration of intravenous bolus epinephrine compared with intramuscular epinephrine J Allergy Clin Immunol Pract., 3 (2014), pp. 76-80

38 Y.S. Xu, M. Kastner, L. Harada, A. Xu, J. Salter, S. Waserman Anaphylaxis-related deaths in Ontario: a retrospective review of cases from 1986 to 2011 Allergy Asthma Clin Immunol., 10 (2014), p. 38

39 N.J.N. Harper, T.M. Cook, T. Garcez, et al. Anaesthesia, surgery, and life-threatening allergic reactions: management and outcomes in the 6th National Audit Project (NAP6) Br J Anaesth., 121 (2018), pp. 172-188

40 M. Kanwar, C.B. Irvin, J.J. Frank, K. Weber, H. Rosman Confusion about epinephrine dosing leading to iatrogenic overdose: a life-threatening problem with a potential solution Ann Emerg Med., 55 (2010), pp. 341-344

41 A. Gouel-Cheron, L. de Chaisemartin, F. Jonsson, et al. Low end-tidal CO2 as a marker of a real-time severity marker of intra-anaesthetic acute hypersensitivity reactions Br J Anaesth., 119 (2017), pp. 908-917

42 L.H. Garvey, B. Belhage, M. Kroigaard, B. Husum, H.J. Malling, H. Mosbech Treatment with epinephrine (adrenaline) in suspected anaphylaxis during anesthesia in Denmark Anesthesiology., 115 (2011), pp. 111-116

43 A. Gouel-Cheron, A. Harpan, P.M. Mertes, D. Longrois Management of anaphylactic shock in the operating room Presse Med., 45 (2016), pp. 774-783

44 P. Turner, E. Jerschow, T. Umasunthar, R. Lin, D.E. Campbell, R.J. Boy Fatal anaphylaxis: mortality rate and risk factors J Allergy Clin Immunol Pract., 5 (2017), pp. 1169-1178

45 G.M. Weiss, A.D. Fandrick, D. Sidebotham Successful rescue of an adult with refractory anaphylactic shock and abdominal compartment syndrome with venoarterial extracorporeal membrane oxygenation and bedside laparotomy Semin Cardiothor Vasc Anesthesia., 19 (2015), pp. 66-70

46 R.C. Clarke, P.H. Sadleir, P.R. Platt The role of sugammadex in the development and modification of an allergic response to rocuronium: evidence from a cutaneous model Anaesthesia., 67 (2012), pp. 266-273

47 P.R. Platt, R.C. Clarke, G.H. Jonson, P.H. Sadleir Efficacy of sugammadex in rocuronium-induced or antibiotic-induced anaphylaxis. A case-control study Anaesthesia., 70 (2015), pp. 1264-1267

48 D.L. Hepner, M. Castells, C. Mouton-Faivre, P. Dewachter Anaphylaxis in the clinical setting of obstetric anesthesia: a literature review Anesth Analg., 117 (2013), pp. 1357-1367

49 S.J. McCall, K.J. Bunch, P. Brocklehurst, et al. The incidence characteristics, managements and outcomes of anaphylaxis in pregnancy: a population-based descriptive study BJOG., 125 (2018), pp. 965-971

50 E.J. Lavonas, I.R. Drennan, A. Gabrielli, et al. Part 10: special circumstances of resuscitation 2015 American Heart Association guidelines update for cardiopulmonary resuscitation and emergency cardiovascular care Circulation., 132 (suppl 2) (2015), pp. S501-S518

51 S.M. Kinsella, B. Carvalho, R.A. Dyer, et al. International consensus statement on the management of hypotension with vasopressor during cesarean section under spinal anesthesia Anaesthesia., 73 (2018), pp. 71-92

52 D. Hood, D. Dewan, F. James Maternal and fetal effects of epinephrine in gravid ewes Anesthesiology. (1986), pp. 64-610

53 M.C. Mushambi, S. Jaladi Airway management and training in obstetric anaesthesia Curr Opin Anaesthesiol., 29 (2016), pp. 261-267

54 F.E.R. Simmons, M. Schatz Anaphylaxis during pregnancy J Allergy Clin Immunol., 130 (2012), pp. 597-605

55 S. Lipman, S. Cohen, S. Einav, et al. The Society of Obstetric Anesthesia and perinatology Consensus Statement on the management of cardiac arrest in pregnancy Anesth Analg., 118 (2014), pp. 1003-1016

56 B. Stepanovic, D. Sommerfield, M. Lucas, B.S. von Ungern-Sternberg An update on allergy and anaphylaxis in pediatric anesthesia Paediatr Anaesth., 29 (2019), pp. 892-900

57 E. Khaleva, A. Franz, L.H. Garvey, A. Ylescupidez, H.T. Bahnson, G. du Toit Perioperative anaphylaxis in children: etiology, time sequence, and patterns of clinical reactivity Pediatr Allergy Immunol., 31 (2020), pp. 85-94

58 N.J.N. Harper, T.M. Cook, T. Garcez, et al. Anaesthesia, surgery, and life-threatening allergic reactions: epidemiology and clinical features of perioperative anaphylaxis in the 6th National Audit Project Br J Anaesth., 121 (2018), pp. 159-171

59 M. Thomas, N. Harper, T. Cook Paediatric anaesthesia In: Anaesthesia, surgery and life-threatening allergic reactions: from the Report and findings of the 6th National Audit Project, Royal College of Anaesthetists (2018), pp. 216-221

60 A.V. Michavila Gomez, M.T. Belver Gonzalez, N.C. Alvarez, et al. Perioperative anaphylactic reactions: Review and procedure protocol in paediatrics Allergol Immunopathol (Madr)., 43 (2015), pp. 203-214

61 P.M. Mertes, F. Alla, P. Trechot, Y. Auroy, E. Jougla, P. Groupe d’Etudes des Reactions Anaphylactoides Anaphylaxis during anesthesia in France: an 8- year national survey J Allergy Clin Immunol., 128 (2011), pp. 366-373

62 M. Kerton, A. Jones, C. Gough, R. Hardy, F.E. Kelly Paediatric anaphylaxis management: training staff to draw up the correct dose of epinephrine Br J Anaesth., 120 (2018), pp. 881-882

63 S.H. Sicherer, E.S. Simons Epinephrine for first-aid management of anaphylaxis Pediatrics., 139 (2017), p. e20164006

64 A. Muraro, G. Roberts, A. Clark, et al. The management of anaphylaxis in childhood: position paper of the European academy of allergology and clinical immunology Allergy., 62 (2007), pp. 857-871

65 M.C. Liu, D. Proud, L.M. Lichtenstein, et al. Effects of prednisone on the cellular responses and release of cytokines and mediators after segmental allergen challenge of asthmatic subjects J Allergy Clin Immunol., 108 (2001), pp. e29-e38

66 W. Alqurashi, A.K. Ellis Do corticosteroids prevent biphasic anaphylaxis? J Allergy Clin Immunol., 5 (2017), pp. 1194-1205

67 J. Vitte Human mast cell tryptase in biology and medicine Mol Immunol., 63 (2015), pp. 18-24

68 W. Egner, T.M. Cook, T. Garcez, et al. Specialist perioperative allergy clinic services in the UK 2018: Results from the Royal College of Anaesthetists Sixth National Audit Project (NAP6) investigation of perioperative anaphylaxis Clin Exp Allergy., 48 (2018), pp. 846-861

69 J. Vitte, L. Amadei, M. Gouitaa, et al. Paired acute-baseline serum tryptase levels in perioperative anaphylaxis: an observational study Allergy., 74 (2019), pp. 1157-1165

70 R.L. Baretto, S. Beck, J. Heslegrave, C. Melchior, O. Mohamed, A. Ekbote, et al. Validation of international consensus equation for acute serum total tryptase in mast cell activation: a perioperative perspective Allergy, 72 (2017), p. 20314

71 D. Laroche, P. Gomis, E. Gallimidi, J.M. Malinowsky, P.M. Mertes Diagnostic value of histamine and tryptase concentrations in severe anaphylaxis with shock or cardiac arrest during anesthesia Anesthesiology., 121 (2014), pp. 272-279

72 L.H. Garvey Practical aspects of perioperative anaphylaxis Trends Anaesth Crit Care., 3 (2013), pp. 320-326

73 P.H.M. Sadleir, R.C. Clarke, P.R. PLatt Consequences of proceeding surgery after resuscitation from intra-operative anaphylaxis Anaesthesia., 73 (2018), pp. 32-39

74 M. Guilarte, A. Sala-Cunill, O. Luengo, M. Labrador-Horrillo, V. Cardona The mast cell, contact, and coagulation system connection in anaphylaxis Frontiers in Immunol., 8 (2017), p. 846

75 L.H. Garvey Perioperative hypersensitivity reactions: diagnosis, treatment and evaluation Curr Treat Options Allergy., 3 (2016), pp. 113-128

76 Conselho Federal de Medicina. Resolução 2.174, de 14 de dezembro de 2017. Dispões sobre a prática do ato anestésico e revoga a Resolução CFM 1.806/2006. Diário Oficial da União. Publicado em 27/02/2018. Edição 39. Seção 1. Páginas 75-84.

77 I.S. Christiansen, P. Pederson, M. Kroigaard, H. Mosbech, L.H. Garvey Anaphylaxis to intravenous gentamicin with suspected sensitization through gentamicina-loaded bone cement J Allergy Clin Immunol Pract., 4 (2016), p. 1258

78 E. Moissiev, E. Levinger Anaphylactic reaction following intracameral cefuroxime injection during cataract surgery J Cataract Refract Surg., 39 (2013), pp. 1432-1434

79 W. Egner, R.R. Sargur, A. Shrimpton, M. York, K. Green A 17-year experience in perioperative anaphylaxis 1998-2015: harmonizing optimal detection of mast cell mediator release Clin Exp Allergy., 46 (2016), pp. 1465-1473

80 S.C. Beck, T. Wilding, R.J. Buka, R.L. Baretto, A.P. Huissoon, M.T. Krishna Biomarkers in human anaphylaxis: a critical appraisal of current evidence and perspectives Front Immunol., 10 (2019), pp. 1-11

81 J. Soar, R. Pumphrey, A. Cant, et al. Emergency treatment of anaphylactic reactions – Guidelines for healthcare providers Resuscitation., 77 (2008), pp. 157-169

82 A. Muraro, G. Roberts, M. Worm, et al. Anaphylaxis: Guidelines from the European Academy of Allergy and Clinical Immunology Allergy., 69 (2014), pp. 1026-1045

83 P. Demoly, N.F. Adkinson, K. Brockow, et al. International consensus on drug allergy Allergy., 69 (2014), pp. 420-437

84 R.J. Scolaro, H.M. Crilly, E.J. Maycock, et al. The Australian and New Zealand anaesthetic allergy group perioperative anaphylaxis investigation guidelines Anaesth Intensive Care., 45 (2017), pp. 543-555

85 P. Demoly, N.F. Adkinson, K. Brockow, et al. International consensus on drug allergy Allergy., 69 (2014), pp. 420-437

86 M. Kroigaard, L.H. Garvey, T. Menné, B. Husum Allergic reactions in anaesthesia: are suspected causes confirmed on subsequent testing? Br J Anaesth., 95 (2005), pp. 486-571

87 A.C. Guyer, R.R. Saff, M. Conroy, et al. Comprehensive allergy evaluation is useful in the subsequent care of patients with drug hypersensitivity reactions during anesthesia J Allergy Clin Immunol Pract., 3 (2015), pp. 94-100

88 A.M. Chiriac, C. Tacquarad, N.B. Fadhel, et al. Safety of subsequent general anesthesia in patients allergic to neuromuscular blocking agents: value of allergy skin tests Br J Anaesth., 120 (2018), pp. 1437-1440

89 N. Harper, T. Cook Anaesthesia, surgery and life-threatening allergic reactions - Summary of main findings Br J Anaesth., 121 (2018), pp. 183-191

90 L.H. Garvey, D.G. Ebo, P.M. Mertes, et al. An EAACI position paper on the investigation of perioperative immediate hypersensitivity reactions Allergy., 74 (2019), pp. 1872-1884

91 N. Cabañes, J.M. Igea, B. de la Hoz, et al. Latex allergy: position paper J Investig Allergol Clin Immunol., 22 (2012), pp. 313-330

92 Silva Jr JB. Resolução RDC n° 37, de 26 de agosto de 2015. Ministério da Saúde/Agência Nacional de Vigilância Sanitária/Diretoria Colegiada. Dispõe sobre a padronização de frases de declaração de conteúdo de látex de borracha natural em rótulos de dispositivos médicos. Diário Oficial da União. Edição 164, Seção 1, Página 46.

93 S. Marinho Perioperative anaphylaxis - Time for a NAP6! Clin Exp Allergy, 48 (2018), pp. 1252-1254

94 L. Cabrini, M. Baiardo Redealli, L. Ball, et al. Awake fiberoptic intubation protocols in the operating room for anticipated difficult airway: a systematic review and meta-analysis of randomized controlled trials Anesth Analg., 128 (2019), pp. 971-980

95 M. Madhere, D. Vangura, A. Saidov Dexmedetomidine as sole agent for awake fiberoptic intubation in a patient with local anesthetic allergy J Anaesth., 25 (2011), pp. 592-594

96 P.M. Mertes, F. De Blay, S. Dong Risque allergique en anesthésie Presse Med., 42 (2013), pp. 269-279

97 P.H.M. Sadleir, R.C. Clarke, D.L. Bunning, P.R. Platt Anaphylaxis to neuromuscular blocking drugs: incidence and cross-reactivity in Western Australia from 2002 to 2011 Br J Anaesth., 110 (2013), pp. 981-987

98 M.S. Opstrup, L.K. Poulsen, H.J. Malling, B.M. Jensen, L.H. Garvey Dynamics of specific IgE in chlorhexidine allergic patients with and without accidental re-exposure Clin Exp Allergy., 46 (2016), pp. 1090-1098

99 R.J. Mullins The relationship between red meat allergy and sensitization to gelatin and galactose-alpha-1,3-galactose J Allergy Clin Immunol., 125 (2012), pp. 1334-1342

100 D.G. Ebo, M.M. Fischer, M.M. Hagendorens, C.H. Bridts, W.J. Stevens Anaphylaxis during anaesthesia: diagnostic approach Allergy., 62 (2007), pp. 471-487

101 M.V. Bhole, A.L. Manson, S.L. Seneviratne, S.A. Misbah IgE-mediate allergy to local anaesthetic: separating fact from perception: a UK perspective Br J Anaesth., 108 (2012), pp. 903-911

102 B.J. Akhavan, U.A. Osborn, R. Mathew Anaphylactic reaction to ethylene oxide in a hemodialysis patient SAGE Open Med Case Rep., 7 (2019) 2050313X19838744

103 M.S. Opstrup, H. Mosbech, L.H. Garvey Allergic sensitization to ethyelene oxide in patients with suspected allergic reactions during surgery and anesthesia J Investig Allergol Clin Immunol., 20 (2010), pp. 69-70

104 L.H. Garvey Old, new and hidden causes of perioperative hypersensitivity Curr Pharm Des., 22 (2016), pp. 6814-6824

105 S. Bache, J.T. Petersen, L.H. Garvey Anaphylaxis to ethylene oxide – a rare and overlooked phenomenon? Acta Anaesthesiol Scand., 55 (2011), pp. 1279-1282

106 A. Listyo, K.S. Hofmaeier, O. Bandschapp, T. Erb, C.C. Hasler, A.J. Bircher Severe anaphylactic shock due to ethylene oxide in a patient with myelomeningocele: successful exposure prevention and pretreatment with omalizumab Anesth Analg Case Rep., 2 (2014), pp. 3-6