Brazilian Journal of Anesthesiology
https://bjan-sba.org/article/doi/10.1016/j.bjane.2018.03.001
Brazilian Journal of Anesthesiology
Scientific Article

Adverse postoperative cognitive disorders: a national survey of portuguese anesthesiologists

Distúrbios cognitivos adversos no pós-operatório: uma pesquisa nacional de anestesiologistas portugueses

Maria J. Susano; Liliana Vasconcelos; Tiago Lemos; Pedro Amorim; Fernando J. Abelha

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Abstract

Abstract Background and objectives Postoperative delirium and postoperative cognitive dysfunction are some of the most common complications in older surgical patients and are associated with adverse outcomes. The aim of this study was to evaluate portuguese anesthesiologists’ perspectives and knowledge about adverse postoperative cognitive disorders, and routine clinical practice when caring for older surgical patients. Methods We used a prospective online survey with questions using a Likert scale from 1 to 5 (completely disagree to completely agree), or yes/no/don’t know answer types. Potential participants were portuguese anesthesiologists working in hospitals affiliated with the portuguese national health system and private hospitals. Results We analyzed 234 surveys (17.7% of total potential respondents). The majority believed that the risk of cognitive side effects should be considered when choosing the type of anesthesia (87.6%) and that preoperative cognitive function should be routinely assessed (78.6%). When caring for an agitated and confused patient postoperatively, 62.4% would first administer an analgesic and 11.1% an anxiolytic. Protocols to screen and manage postoperative cognitive disorders are rarely used. Nearly all respondents believe that postoperative delirium and postoperative cognitive dysfunction are neglected areas in anesthesiology. Conclusions Overall, participants perceive postoperative cognitive disorders as important adverse outcomes following surgery and anesthesia are aware of the main risk factors for their development but may lack information on prevention and management of postoperative delirium. The majority of hospitals do not have protocols regarding preoperative cognitive assessment, diagnosis, management or follow-up of patients with delirium and postoperative cognitive dysfunction.

Keywords

Postoperative period, Neurocognitive disorders, Delirium, Cognitive dysfunction, Surveys and questionnaires

Resumo

Resumo Justificativa e objetivos O delírio pós-operatório e a disfunção cognitiva pós-operatória são algumas das complicações mais comuns em pacientes cirúrgicos mais idosos e estão associados a desfechos adversos. O objetivo deste estudo foi avaliar as perspectivas e conhecimentos de anestesiologistas portugueses sobre distúrbios cognitivos pós-operatórios e a prática clínica de rotina ao cuidar de pacientes cirúrgicos idosos. Métodos Pesquisa prospectiva on-line com perguntas usando uma escala Likert de 1–5 (discordo completamente–concordo completamente), ou respostas como sim/não/não sei. Os potenciais participantes eram anestesiologistas portugueses que trabalhavam em hospitais afiliados ao sistema nacional de saúde português e hospitais privados. Resultados Analisamos 234 resultados (17,7% do total dos potenciais respondentes). A maioria acreditava que o risco de efeitos colaterais cognitivos deveria ser considerado ao escolher o tipo de anestesia (87,6%) e que a função cognitiva pré-operatória deveria ser rotineiramente avaliada (78,6%). Ao cuidar de um paciente agitado e confuso no pós-operatório, 62,4% administraram primeiro um analgésico e 11,1% um ansiolítico. Protocolos para detectar e tratar distúrbios cognitivos pós-operatórios são raramente usados. Quase todos os entrevistados acreditam que o delírio pós-operatório e a disfunção cognitiva pós-operatória são áreas negligenciadas na anestesiologia. Conclusões Em geral, os participantes percebem os distúrbios cognitivos pós-operatórios como importantes resultados adversos após a cirurgia e anestesia, estão cientes dos principais fatores de risco para seu desenvolvimento, mas podem não ter informações sobre como prevenir e tratar o delírio pós-operatório. A maioria dos hospitais não possui protocolos de avaliação cognitiva pré-operatória, diagnóstico, tratamento ou acompanhamento de pacientes com delírio e disfunção cognitiva no pós-operatório.

Palavras-chave

Período pós-operatório, Distúrbios neurocognitivos, Disfunção cognitiva, Pesquisas e questionários

References

Etzioni DA, Liu JH, Maggard MA. The aging population and its impact on the surgery workforce. Ann Surg. 2003;238:170-7.

Hamel MB, Henderson WG, Khuri SF. Surgical outcomes for patients aged 80 and older: morbidity and mortality from major noncardiac surgery. J Am Geriatr Soc. 2005;53:424-9.

Monk TG, Weldon BC, Garvan CW. Predictors of cognitive dysfunction after major noncardiac surgery. Anesthesiology. 2008;108:18-30.

Marcantonio ER. Postoperative delirium: a 76-year-old woman with delirium following surgery. JAMA. 2012;308:73-81.

Bruce AJ, Ritchie CW, Blizard R. The incidence of delirium associated with orthopedic surgery: a meta-analytic review. Int Psychogeriatr. 2007;19:197-214.

Whitlock EL, Vannucci A, Avidan MS. Postoperative delirium. Minerva Anestesiol. 2011;77:448-56.

Moller JT, Cluitmans P, Rasmussen LS. Long-term postoperative cognitive dysfunction in the elderly ISPOCD1 study, ISPOCD investigators. International Study of Post-Operative Cognitive Dysfunction. Lancet. 1998;351:857-61.

Steinmetz J, Christensen KB, Lund T. Long-term consequences of postoperative cognitive dysfunction. Anesthesiology. 2009;110:548-55.

Silverstein JH, Deiner SG. Perioperative delirium and its relationship to dementia. Prog Neuropsychopharmacol Biol Psychiatry. 2013;43:108-15.

Postoperative delirium in older adults: best practice statement from the American Geriatrics Society. J Am Coll Surg. 2015;220:136-48.

Rudolph JL, Inouye SK, Jones RN. Delirium: an independent predictor of functional decline after cardiac surgery. J Am Geriatr Soc. 2010;58:643-9.

Martin BJ, Buth KJ, Arora RC. Delirium: a cause for concern beyond the immediate postoperative period. Ann Thorac Surg. 2012;93:1114-20.

Abelha FJ, Luis C, Veiga D. Outcome and quality of life in patients with postoperative delirium during an ICU stay following major surgery. Crit Care. 2013;17:R257.

Aldecoa C, Bettelli G, Bilotta F. European Society of Anaesthesiology evidence-based and consensus-based guideline on postoperative delirium. Eur J Anaesthesiol. 2017;34:192-214.

Jildenstal PK, Rawal N, Hallen JL. Perioperative management in order to minimise postoperative delirium and postoperative cognitive dysfunction: Results from a Swedish web-based survey. Ann Med Surg (Lond). 2014;3:100-7.

Lemos LJP, Viana J, Assunção JP. Censos anestesiologia – 2014 | Relatório final Census anesthesiology – 2014 | Final report board of the Portuguese Anesthesiology of the Portuguese Medical Association. Rev Soc Port Anestesiol. 2015;24:41-52.

Pandit JJ, Cook TM, Jonker WR. A national survey of anaesthetists (NAP5 baseline) to estimate an annual incidence of accidental awareness during general anaesthesia in the UK. Br J Anaesth. 2013;110:501-9.

Radtke FM, Franck M, Hagemann L. Risk factors for inadequate emergence after anesthesia: emergence delirium and hypoactive emergence. Minerva Anestesiol. 2010;76:394-403.

Evered L, Scott DA, Silbert B. Postoperative cognitive dysfunction is independent of type of surgery and anesthetic. Anesth Analg. 2011;112:1179-85.

Girard TD, Jackson JC, Pandharipande PP. Delirium as a predictor of long-term cognitive impairment in survivors of critical illness. Crit Care Med. 2010;38:1513-20.

Pandharipande PP, Girard TD, Jackson JC. Long-term cognitive impairment after critical illness. N Engl J Med. 2013;369:1306-16.

Greene NH, Attix DK, Weldon BC. Measures of executive function and depression identify patients at risk for postoperative delirium. Anesthesiology. 2009;110:788-95.

Heng M, Eagen CE, Javedan H. Abnormal mini-cog is associated with higher risk of complications and delirium in geriatric patients with fracture. J Bone Joint Surg Am. 2016;98:742-50.

Robinson TN, Wu DS, Pointer LF. Preoperative cognitive dysfunction is related to adverse postoperative outcomes in the elderly. J Am Coll Surg. 2012;215:12-7.

Ehlenbach CC, Tevis SE, Kennedy GD. Preoperative impairment is associated with a higher postdischarge level of care. J Surg Res. 2015;193:1-6.

Oresanya LB, Lyons WL, Finlayson E. Preoperative assessment of the older patient: a narrative review. JAMA. 2014;311:2110-20.

Silbert B, Evered L, Scott DA. Preexisting cognitive impairment is associated with postoperative cognitive dysfunction after hip joint replacement surgery. Anesthesiology. 2015;122:1224-34.

Ganguli M, Rodriguez E, Mulsant B. Detection and management of cognitive impairment in primary care: the steel valley seniors survey. J Am Geriatr Soc. 2004;52:1668-75.

Chodosh J, Petitti DB, Elliott M. Physician recognition of cognitive impairment: evaluating the need for improvement. J Am Geriatr Soc. 2004;52:1051-9.

Chow WB, Rosenthal RA, Merkow RP. Optimal preoperative assessment of the geriatric surgical patient: a best practices guideline from the American College of Surgeons National Surgical Quality Improvement Program and the American Geriatrics Society. J Am Coll Surg. 2012;215:453-66.

Partridge JS, Dhesi JK, Cross JD. The prevalence and impact of undiagnosed cognitive impairment in older vascular surgical patients. J Vasc Surg. 2014;60:1002-11.

Axley MS, Schenning KJ. Preoperative Cognitive and frailty screening in the geriatric surgical patient: a narrative review. Clin Ther. 2015;37:2666-75.

Long LS, Shapiro WA, Leung JM. A brief review of practical preoperative cognitive screening tools. Can J Anaesth. 2012;59:798-804.

Moyce Z, Rodseth RN, Biccard BM. The efficacy of peri-operative interventions to decrease postoperative delirium in non-cardiac surgery: a systematic review and meta-analysis. Anaesthesia. 2014;69:259-69.

Santarpino G, Fasol R, Sirch J. Impact of bispectral index monitoring on postoperative delirium in patients undergoing aortic surgery. HSR Proc Intensive Care Cardiovasc Anesth. 2011;3:47-58.

Sieber FE, Zakriya KJ, Gottschalk A. Sedation depth during spinal anesthesia and the development of postoperative delirium in elderly patients undergoing hip fracture repair. Mayo Clin Proc. 2010;85:18-26.

Fritz BA, Kalarickal PL, Maybrier HR. Intraoperative electroencephalogram suppression predicts postoperative delirium. Anesth Analg. 2016;122:234-42.

Soehle M, Dittmann A, Ellerkmann RK. Intraoperative burst suppression is associated with postoperative delirium following cardiac surgery: a prospective, observational study. BMC Anesthesiol. 2015;15:61.

Deiner S, Luo X, Silverstein JH. Can intraoperative processed EEG predict postoperative cognitive dysfunction in the elderly?. Clin Ther. 2015;37:2700-5.

Radtke FM, Franck M, Lendner J. Monitoring depth of anaesthesia in a randomized trial decreases the rate of postoperative delirium but not postoperative cognitive dysfunction. Br J Anaesth. 2013;110:i98-i105.

Chan MT, Cheng BC, Lee TM. BIS-guided anesthesia decreases postoperative delirium and cognitive decline. J Neurosurg Anesthesiol. 2013;25:33-42.

Shepherd J, Jones J, Frampton G. Clinical effectiveness and cost-effectiveness of depth of anaesthesia monitoring (E-Entropy, Bispectral Index and Narcotrend): a systematic review and economic evaluation. Health Technol Assess. 2013;17:1-264.

Avidan MS, Jacobsohn E, Glick D. Prevention of intraoperative awareness in a high-risk surgical population. N Engl J Med. 2011;365:591-600.

De J, Wand AP. Delirium screening: a systematic review of delirium screening tools in hospitalized patients. Gerontologist. 2015;55:1079-99.

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