Brazilian Journal of Anesthesiology
https://bjan-sba.org/article/doi/10.1016/j.bjane.2013.09.015
Brazilian Journal of Anesthesiology
Review Article

Is there any benefit in associating neuraxial anesthesia to general anesthesia for coronary artery bypass graft surgery?

Existe algum benefício em associar a anestesia neuroaxial à anestesia geral para revascularização miocárdica?

Fabiano Timbó Barbosa; Célio Fernando de Sousa Rodrigues; Aldemar Araújo Castro; Rafael Martins da Cunha; Tatiana Roa Bezerra Wanderley Barbosa

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Abstract

ABSTRACT BACKGROUND AND OBJECTIVES: The use of neuraxial anesthesia in cardiac surgery is recent, but the hemodynamic effects of local anesthetics and anticoagulation can result in risk to patients. OBJECTIVE: To review the benefits of neuraxial anesthesia in cardiac surgery for CABG through a systematic review of systematic reviews. CONTENT: The search was performed in Pubmed (January 1966 to December 2012), Embase (1974 to December 2012), The Cochrane Library (volume 10, 2012) and Lilacs (1982 to December 2012) databases, in search of articles of systematic reviews. The following variables: mortality, myocardial infarction, stroke, in-hospital length of stay, arrhythmias and epidural hematoma were analyzed. CONCLUSIONS: The use of neuraxial anesthesia in cardiac surgery remains controversial. The greatest benefit found by this review was the possibility of reducing postoperative arrhythmias, but this result was contradictory among the identified findings. The results of findings regarding mortality, myocardial infarction, stroke and in-hospital length of stay did not show greater efficacy of neuraxial anesthesia.

Keywords

General anesthesia, Subarachnoid anesthesia, Thoracic epidural anesthesia, Systematic review, Mortality, Evidence

Resumo

RESUMO JUSTIFICATIVA E OBJETIVOS: O uso da anestesia neuroaxial em cirurgia cardíaca é recente, porém os efeitos hemodinâmicos dos anestésicos locais e a anticoagulação podem trazer riscos aos pacientes. OBJETIVO: Revisar os benefícios da anestesia neuroaxial em cirurgia cardíaca para revascularização miocárdica por meio de uma revisão sistemática de revisões sistemáticas. CONTEÚDO: Foi feita pesquisa nas bases de dados Pubmed (de janeiro de 1966 a dezembro de 2012), Embase (1974 a dezembro 2012), The Cochrane Library (volume 10, 2012) e Lilacs (1982 a dezembro de 2012) em busca de artigos de revisões sistemáticas. Foram analisadas as seguintes variáveis: mortalidade, infarto do miocárdio, acidente vascular cerebral, tempo de internação hospitalar, arritmias e hematoma peridural. CONCLUSÕES: O uso da anestesia neuroaxial para revascularização miocárdica permanece controverso. O maior benefício encontrado por meio desta revisão foi a possibilidade de redução das arritmias pós-operatórias, porém esse resultado foi contraditório entre as evidências identificadas. Os resultados das evidências encontradas referentes à mortalidade, ao infarto do miocárdio, ao acidente vascular cerebral e ao tempo de internação hospitalar não mostraram maior efetividade da anestesia neuroaxial.

Palavras-chave

Anestesia geral, Anestesia subaracnoidea, Anestesia epidural torácica, Revisão sistemática, Mortalidade, Evidências

References

Mangano DT. Assessment of the patient with cardiac disease an anesthesiologist's paradigm. Anesthesiology. 1999;91:1521-6.

Coriat P, Beaussier M. Fast-tracking after coronary artery bypass graft surgery. Anesth Analg. 2001;92:1081-3.

Nygård E, Kofoed KF, Freiberg J. Effects of high thoracic epidural analgesia on myocardial blood flow in patients with ischemic heart disease. Circulation. 2005;111:2165-70.

Beattie WS, Badner NH, Choi PT. Meta-analysis demonstrates statistically significant reduction in postoperative myocardial infarction with the use of thoracic epidural analgesia. Anesth Analg. 2003;97:919-20.

Lagunilla J, Garcia-Bengochea JB, Fernandez AL. High thoracic epidural blockade increases myocardial oxygen avail- ability in coronary surgery patients. Acta Anaesthesiol Scand. 2006;50:780-6.

Ho AM, Chung DC, Joynt GM. Neuraxial blockade and hematoma in cardiac surgery estimating the risk of a rare adverse event that has not (yet) occurred. Chest. 2000;117:551-5.

Chaney MA. Intrathecal and epidural anesthesia and analgesia for cardiac surgery. Anesth Analg. 2006;102:45-64.

Higgins JPT, Green S. Cochrane Handbook for System-atic Reviews of Interventions Version 5.1.0. 2011.

Moher D, Liberati A, Tetzlaff J. Preferred reporting items for systematic reviews and meta-analyses the Prisma state- ment. Ann Intern Med. 2009;151:264-9.

Oxman AD, Guyatt GH. Validation of an index of the quality of review articles. J Clin Epidemiol. 1991;44:1271-8.

Kelly KD, Travers A, Dorgan M, Slater L, Rowe BH. Evaluating the quality of systematic reviews in the emergency medicine literature. Ann Emerg Med. 2001;38:518-26.

Barbosa FT, Castro AA, Miranda CT. Neuraxial anesthesia com- pared to general anesthesia for procedures on the lower half of the body systematic review of systematic reviews. Rev Bras Anestesiol. 2012;62:235-43.

Liu SS, Block BM, Wu CL. Effects of perioperative central neurax- ial analgesia on outcome after coronary artery bypass surgery a meta-analysis. Anesthesiology. 2004;101:153-61.

Zangrillo A, Bignami E, Biondi-Zoccai GG. Spinal analgesia in cardiac surgery a meta-analysis of randomized controlled trials. Cardiothorac Vasc Anesth. 2009;23:813-21.

Svircevic V, van Dijk D, Nierich AP. Meta-analysis of tho- racic epidural anesthesia versus general anesthesia for cardiac surgery. Anesthesiology. 2011;114:271-82.

Gu WJ, Wei CY, Huang DQ. Meta-analysis of randomized controlled trials on the efficacy of thoracic epidural anesthe- sia in preventing atrial fibrillation after coronary artery bypass grafting. BMC Cardiovasc Disord. 2012;12:67.

Chaney MA. Should thoracic epidural/spinal analgesia be used for CABG?. Evidence-based practice of anesthesiology. 2009:424-7.

Mangano DT, Siliciano D, Hollenberg M. Postoperative myocardial ischemia therapeutic trials using intensive analge- sia following surgery. Anesthesiology. 1992;76:342-53.

Liu S, Carpenter RL, Neal MJ. Epidural anesthesia and anal- gesia their role in postoperative outcome. Anesthesiology. 1995;82:1474-506.

Vanstrum GS, Bjornson KM, Ilko R. Postoperative effects of intrathecal morphine in coronary artery bypass surgery. Anesth Analg. 1988;67:261-7.

Chaney MA, Smith KR, Barclay JC. Large-dose intrathe- cal morphine for coronary artery bypass grafting. Anesth Analg. 1996;83:215-22.

Chaney MA, Furry PA, Fluder EM. Intrathecal morphine forcoronary artery bypass grafting and early extubation. AnesthAnalg. 1997;84:241-8.

Chaney MA, Nikolov MP, Blakeman BP. Intrathe-cal morphine for coronary artery bypass graft procedureand early extubation revisited. J Cardiothorac Vasc Anesth. 1999;13:574-8.

Priestley MC, Cope L, Halliwell R. Thoracic epidural anes- thesia for cardiac surgery the effects on tracheal intubation time and length of hospital stay. Anesth Analg. 2002;94:275-82.

Royse C, Royse A, Soeding P. Prospective randomized trial of high thoracic epidural analgesia for coronary artery bypass surgery. Ann Thorac Surg. 2003;75:93-100.

Hansdottir V, Philip J, Olsen MF. Thoracic epidural versus intravenous patient-controlled analgesia after cardiac surgery a randomized controlled trial on length of hospital stay and patient-perceived quality of recovery. Anesthesiology. 2006;104:142-51.

Ho AMH, Chung DC, Joynt GM. Neuraxial blockade and hematoma in cardiac surgery estimating the risk of a rare adverse event that has not (yet) occurred. Chest. 2000;117:551-5.

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