Perioperative morbidity and mortality in the first year of life: a systematic review (1997-2012)

Dora Catré; Maria Francelina Lopes; Joaquim Silva Viana; António Silvério Cabrita

doi:10.1016/j.bjane.2013.03.025

Review Article

Perioperative morbidity and mortality in the first year of life: a systematic review (1997-2012)

Morbimortalidade perioperatória no primeiro ano de idade: revisão sistemática (1997-2012)

Dora Catré; Maria Francelina Lopes; Joaquim Silva Viana; António Silvério Cabrita

http://dx.doi.org/10.1016/j.bjane.2013.03.025 Braz J Anesthesiol, vol.65, n5, p.384-394, 2015

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Abstract

ABSTRACTBACKGROUND AND OBJECTIVES: Although many recognize that the first year of life and specifically the neonatal period are associated with increased risk of anesthetic morbidity and mortality, there are no studies directed to these pediatric subpopulations. This systematic review of the scientific literature including the last 15 years aimed to analyze the epidemiology of morbidity and mortality associated with general anesthesia and surgery in the first year of life and particularly in the neonatal (first month) period.CONTENT: The review was conducted by searching publications in Medline/PubMed databases, and the following outcomes were evaluated: early mortality in the first year of life (<1 year) and in subgroups of different vulnerability in this age group (0-30 days and 1-12 months) and the prevalence of cardiac arrest and perioperative critical/adverse events of various types in the same subgroups.CONCLUSIONS: The current literature indicates great variability in mortality and morbidity in the age group under consideration and in its subgroups. However, despite the obvious methodological heterogeneity and absence of specific studies, epidemiological profiles of morbidity and mortality related to anesthesia in children in the first year of life show higher frequency of morbidity and mortality in this age group, with the highest peaks of incidence in the neonates' anesthesia.

Keywords

Early mortality, Morbidity: cardiac arrest, Perioperative critical events/adverse events, 1-Year old/1-month old children

Resumo

RESUMOJUSTIFICATIVA E OBJETIVOS: Embora muitos reconheçam que a idade inferior a um ano e especificamente o período neonatal estejam associados a maior risco de morbimortalidade anestésica, não existem estudos dirigidos a essas subpopulações pediátricas. Esta revisão sistemática das publicações científicas dos últimos 15 anos teve como objetivo analisar o perfil epidemiológico da morbimortalidade relacionada com a anestesia geral e cirurgia no primeiro ano de idade e em particular no período neonatal (primeiro mês de idade).CONTEúDO: A revisão foi conduzida por pesquisa de publicações nas bases de dados Medline/PubMed. Foram avaliados os seguintes desfechos: mortalidade precoce no primeiro ano de idade (< 1A) e em subgrupos de diferente vulnerabilidade nesta faixa etária (0-30 dias e 1-12 meses) e prevalência de parada cardíaca e eventos críticos/adversos perioperatórios de diversos tipos nos mesmos subgrupos.CONCLUSÕES: A literatura corrente indica grande variabilidade nos índices de mortalidade e morbidade na faixa etária em análise, bem como nos seus subgrupos. No entanto, apesar da óbvia heterogeneidade metodológica e da ausência de estudos específicos, os perfis epidemiológicos de morbimortalidade relacionada com a anestesia de crianças no primeiro ano de idade mostram frequência mais alta de morbimortalidade nessa faixa etária, com os maiores picos de incidência na anestesia de neonatos.

Palavras-chave

Mortalidade precoce, Morbidade: parada cardíaca, Eventos críticos e adversos perioperatórios, Crianças de um ano/um mês de idade

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Perioperative morbidity and mortality in the first year of life: a systematic review (1997-2012)

Morbimortalidade perioperatória no primeiro ano de idade: revisão sistemática (1997-2012)

Dora Catré; Maria Francelina Lopes; Joaquim Silva Viana; António Silvério Cabrita

Abstract

Keywords

Resumo

Palavras-chave

References

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